Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients
Key facts
- Who runs it
- University Hospital, Toulouse
- Trial code
- Status
- Withdrawn
- Started
- 9 Oct 2025
- Ended
- 9 Oct 2025
- Type of study
- Interventional
- Treatments tested
- mEEG assessment
- Record updated
- 29 June 2026
- Why it stopped
- material issue
Who can take part
- Age
- 18 years to 80 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 13 criteriaShow less
Who can take part
- Patients admitted to the intensive care unit with ARDS (according to Berlin criteria)
- Delirium (according to Confusion Assessment Method (CAM)-ICU criteria)
- Membership of a social security scheme
- Signed consent of the referring person
- Discontinuation of any sedative agent for ≥ 72 hours
Who cannot take part
- Recent ICU admission (> 5 days of ICU hospitalization within 6 months prior to current ICU admission)
- Pre-existing psychotic disorders
- Pre-existing cognitive deficits (short Informant Questionnaire on Cognitive Decline in the Elderly (short IQCODE) ≥ 3,4)
- Patients whose delirium cannot be reliably assessed due to blindness, deafness or inability to speak French
- Patients whose life expectancy is unlikely to exceed 24 hours
- Pregnant ans breastfeeding women
- Patients under court protection
- Patients who have already participated in the study
About the trial
What the trial wants to find out
Early cognitive assessment of critically-ill acute respiratory distress syndrome (ARDS) patients with delirium using a multidimensional electrophysiological evaluation battery (mEEG) to identify and characterize the neural correlates of cognitive dysfunctions associated with delirium (vigilance, attention, semantic and lexical processing, self-processing), and to develop a prognostic evaluation of neurocognitive and psychological disorders using an innovative non-behavioral approach.
The group in the trial
- ICU patients with ARDS and deliriumTreatment being tested
ICU patients with ARDS and delirium will be assessed twice: in the acute phase of ICU-related delirium (V1) using an mEEG battery (electrophysiological acquisition at rest and during complex cognitive stimulation), and 6 months ± 2 weeks later (V2) using a multi-domain clinical neurocognitive and psychological assessment battery.
Treatment: mEEG assessment
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients: Diagnostic and Prognostic Electrophysiological Signatures
- Record updated
- 29 June 2026