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NCT06211374Active, not recruiting

Communication Bridge Pilot Study

Communication Bridge: Optimizing an Evidence-based Intervention for Individuals With Primary Progressive Aphasia

Source: ClinicalTrials.gov · Last updated 7 Aug 2025

Brief summary (registry, in English)

The aim of this study is to evaluate the effectiveness and feasibility of evidence-based interventions in individuals living with mild to moderate primary progressive aphasia (PPA) that address communication-focused outcomes.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
12 (estimated)
First submitted
8 Jan 2024
Start date
28 Jun 2024
Primary completion date
31 May 2026
Lead sponsor
University of Chicago
NCT number
NCT06211374

What you commit to

  • Study type: Interventional
  • Planned participants: 12
  • From 28 Jun 2024 to the primary completion date, 31 May 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Participation is co-enrolled in an outside speech language therapy program during the study course.

Other illness

  • A dementia diagnosis other than Primary Progressive Aphasia
  • Communication partners will be excluded if they have a pre-existing communication impairment that would affect study participation (e.g., aphasia, dementia) Medical records will be requested and reviewed to determine eligibility

Who the study is looking for

  • Meets diagnostic criteria for PPA based on neurologist and supporting medical assessments (extracted from medical records)
  • English as primary language used in daily communication activities (by self-report)
  • Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report)
  • Adequate vision (aided or unaided) for reading a newspaper, or other functional materials (by self-report)
  • Able to pass technology screening and demonstrates sufficient knowledge for use of video conference and Communication Bridge™ web application use (with or without training)
  • Geriatric Depression Scale score ≤ 9
  • Mild-moderate PPA informed by a structured interview with a speech-language pathologist and a standardized testing battery.
  • 18+ years of age
  • English as primary language used in daily communication activities (by self-report)
  • Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report)
  • Able to pass technology screening\* and demonstrates sufficient knowledge for use of video conference and Communication Bridge™ web application use (with or without training)

Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Chicago - American School Building
Coordinator of this site? Confirm its status
ChicagoUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.