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Taking people in ChinaNo phase

Comparing two exercise programs before lung cancer surgery

Tests two intensities of pre-surgery exercise in adults with lung cancer.

Key facts

Who runs it
Guangdong Provincial People's Hospital
Where
Guangzhou, ChinaSee the site
Trial code
Registry title
Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients
Status
Recruiting
People taking part
100 people, planned
Started
23 Jan 2024
Expected to end
31 Jul 2027
Type of study
Interventional, 3 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • moderate-intensity continuous training
  • high-intensity interval training
Record updated
3 August 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with suspected or confirmed lung cancer who are scheduled for surgery and have a moderate-to-high risk of problems around the operation.

Age
Over 18 years
Sex
Men and women
Disease stage
Suspected or confirmed primary lung cancer with surgery planned. Moderate-to-high risk around surgery: FEV1 below 60% of predicted value (wedge) or ppo FEV1 below 60% of predicted value (lobectomy/segmentectomy) or VO2peak below 20 ml/kg/min.

Main reasons for not taking part

  • Other cancer now or in the past
  • Life expectancy less than 1 year
  • Dementia, infirmity, or being unable to take part in exercise
  • Irregular vital signs (heart rate, blood pressure, temperature, oxygen level)
  • Taking part in another clinical trial

The registry criteria, word for word

Show all 12 criteriaShow less

Who can take part

  • Age>18 years
  • Suspected or confirmed primary lung cancer with scheduled surgical treatment
  • Moderate-to-high perioperative risk, defined as FEV1<60% of predicted value (wedge) or ppo FEV1<60% of predicted value (lobectomy/segmentectomy) or VO2peak<20 ml/kg/ min
  • Sign informed consent and accept to comply with the requirements of the study protocol
  • Completion of a baseline Complete cardiopulmonary exercise testing (CPET)

Who cannot take part

  • Concurrent or previous history of other malignant tumors
  • Dementia; infirmity; or inability to participate in sports (musculoskeletal limitations, namely, injuries, frailty, and weakness)
  • Irregular vital signs (heart rate: < 40 or > 120 bpm at rest; blood pressure: systolic blood pressure > 200 mm Hg or diastolic pressure > 110 mm Hg; T: ≥ 38.5 or ≤ 36◦C; SpO2 ≤ 90%)
  • Life expectancy less than 1 year
  • Inability to maintain exercise training
  • Currently enrolling in any other clinical trials
  • Patient refusal

Where in China

  • Guangdong Provincial People's HospitalGuangzhou, ChinaContact: Huan MaTaking people

About the trial

What the trial wants to find out

The goal of this clinical trail is to compare the effects of preoperative exercise training of different intensities on short-term cardiorespiratory function and postoperative outcomes in patients scheduled for lung resections.

The 3 groups in the trial

  • Moderate-intensity Continuous Training (MICT) GroupTreatment being tested

    MICT plan is containing usual care protocol and additional complete a total of 12 supervised moderate-intensity continuous training sessions in 2 weeks.

    Treatment: moderate-intensity continuous training

  • High-intensity Interval Training (HIIT) GroupTreatment being tested

    HIIT plan is containing usual care protocol and additional complete a total of 12 supervised high-intensity interval training training sessions in 2 weeks.

    Treatment: high-intensity interval training

  • Usual care groupNo study treatment, for comparison

    Usual care includes standard preoperative assessments and receive routine preoperative health education according to institutional practice

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients(PRE-EXELUCA): a Prospective Randomized Controlled Clinical Trial
Plain-language title
Comparing two exercise programs before lung cancer surgeryGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
3 August 2026