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Pharmacogenomics of Stimulant Treatment Response

Key facts

Who runs it
University of Calgary
Where
Canada1 site in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
400 people, planned
Started
1 Apr 2024
Expected to end
31 Dec 2028
Type of study
Observational
Record updated
29 October 2026

Who can take part

Age
6 years to 24 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 12 criteriaShow less

Who can take part

  • Patients will be eligible for participation if all the following are true
  • Aged 6 - 24 years
  • Located in Canada
  • Primary diagnosis of ADHD (all types)
  • Starting Methylphenidate (excluding immediate release forms) treatment

Who cannot take part

  • Psychotherapy or brain stimulation-based therapy initiated within 8 weeks of referral or plans to initiate/change these types of therapies during the study
  • Co-occurring psychotic, bipolar or eating disorders
  • An intellectual disability, or diagnosis of autism spectrum disorder (ASD) or tics/Tourette disorders
  • History of liver or bone marrow (hematopoietic cell) transplant as these events can result in ambiguous genomic results
  • Patients will be excluded from participation if any of the following are true
  • Significant risk of suicide
  • Past 12-month high-risk alcohol or substance use defined as monthly or more frequent use

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 6 and 24 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

The "Pharmacogenomics of Stimulant Treatment Response" (PGx-STaR) study aims to identify genetic profiles related to methylphenidate treatment outcomes in children and adolescents aged 6-24 with Attention deficit/hyperactivity disorder (ADHD).

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Pharmacogenomics of Stimulant Treatment Response in Children and Adolescents With Attention-Deficit/ Hyperactivity Disorder
Fit questions
Built from NCT06221358, who can take part
Record updated
29 October 2026