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WithdrawnPhase 1

Semaglutide and Polycystic Ovarian Syndrome: an Emerging Treatment Strategy

Reason given: IRB did not approve

Key facts

Phase
Phase 1

Trial details

Who runs it
Methodist Health System
Trial code
NCT06222437
Record updated
23 March 2026
Original description
The purpose of this study is to investigate the effect of semaglutide in women with Polycystic Ovarian Syndrome(PCOS ) and determine potential therapeutic benefits.Read full original descriptionShow less

The purpose of this study is to investigate the effect of semaglutide in women with Polycystic Ovarian Syndrome(PCOS ) and determine potential therapeutic benefits.

Inclusion: Age 18-45; Body mass index(BMI) > 30; Diagnosis of PCOS; Normal thyroid stimulating hormone, prolactin, follicle-stimulating hormone (FSH), estradiol, and normal progesterone.

Exclusion: Medications excluded: any hormone-containing contraceptive - oral contraceptive pills, Progesterone-only pill, depo-provera, oral provera, progesterone-containing intrauterine contraceptive device; Letrozole, clomiphene citrate, FSH therapy; 5α reductase inhibitors; Androgen receptor blockers; Insulin; Hysterectomy; Endometrial ablation.

ClinicalTrials.gov NCT06222437