Comparing two imaging guides for heart stent placement during heart attack
Compares two methods guiding stent placement in people having a heart attack.
Plain-language title generated from the registry record
Registry title: OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts
Key facts
- Where
- Daegu, Gwangju, Iksan, Incheon, Jeju City, Jeonju, Jinju, Seoul, Suncheon, Uijeongbu-si, and Ulsan, South KoreaSee the 18 sites
Where in South Korea
- Daegu Catholic University Medical CenterDaegu, South KoreaTaking people
- Kyungpook National University HospitalDaegu, South KoreaTaking people
- Yeungnam University Medical CenterDaegu, South KoreaTaking people
- Chonnam National UniversityGwangju, South KoreaTaking people
- Wonkwang University HospitalIksan, South KoreaTaking people
- International St. Mary's HospitalIncheon, South KoreaTaking people
- Jeju National University HospitalJeju City, South KoreaTaking people
- jeonbuk National University HospitalJeonju, South KoreaTaking people
- Gyeongsang National University HospitalJinju, South KoreaTaking people
- Chung ang University HospitalSeoul, South KoreaTaking people
- Ewha Womans University Mokdong HospitalSeoul, South KoreaTaking people
- Ewha Womans University Seoul HospitalSeoul, South KoreaTaking people
- Korea University Guro HospitalSeoul, South KoreaTaking people
- Kyung Hee University HospitalSeoul, South KoreaTaking people
- Samsung Medical CenterSeoul, South KoreaTaking people
- St.Carollo HospitalSuncheon, South KoreaTaking people
- Uijeongbu ST. Mary's HospitalUijeongbu-si, South KoreaTaking people
- Ulsan University HospitalUlsan, South KoreaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Chonnam National University Hospital
- Trial code
- NCT06227754
- Record updated
- 8 May 2026
- Original description
The aim of the study is to compare clinical outcomes between optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).Read full original descriptionShow less
Randomized Controlled Trial of Optical Coherence Tomography Versus Angiography for Culprit Lesion Revascularization in Patients With Acute Myocardial Infarction
The aim of the study is to compare clinical outcomes between optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).
Inclusion: Subject must be at least 19 years of age; Acute ST-segment elevation myocardial infarction (STEMI); *STEMI: ST-segment elevation ≥0.1 mV in ≥2 contiguous leads or documented newly developed left bundle-branch block1; Primary percutaneous coronary intervention (PCI) in < 12 h after the onset of symptoms for STEMI patients; Subject is able to verbally confirm understandings of risks, benefits and treatment alternatives of receiving invasive physiologic evaluation and PCI and he/she or his/her legally authorized representative provides written informed consent prior to any study related procedure.
Exclusion: Known true anaphylaxis to contrast medium (not allergic reaction but anaphylactic shock); Non-cardiac co-morbid conditions are present with life expectancy <2 year or that may result in protocol non-compliance (per site investigator's medical judgment); Creatinine clearance ≤30 ml/min/1.73 m2 and not on dialysis (chronic dialysis dependent patients are eligible for enrolment regardless of creatinine clearance); Target lesions not amenable for PCI by operators' decision; Ostial lesions located in left main vessel or right coronary artery (left main body or distal bifurcation lesions can be enrolled by operator's discretion); Cardiogenic shock (Killip class IV) at presentation; Intolerance to Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Heparin, or Everolimus; Pregnancy or breast feeding; Unwillingness or inability to comply with the procedures described in this protocol.