Stress Management Training Compared With Yoga in Adults With Depression
Compares a stress resilience training program with yoga in adults with major depression.
Plain-language title generated from the registry record
Registry title: Stress Management in Depressive Disorder: Resilience Training vs. Yoga: Biological, Epigenetic, and Brain Correlates
Key facts
- Where
- Innsbruck, AustriaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06229652, who can take part
Where in Austria
- Medical University InnsbruckInnsbruck, AustriaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Medical University Innsbruck
- Trial code
- NCT06229652
- Record updated
- 5 March 2024
- Original description
The aim of this clinical trial is to evaluate the effects of a Resilience and Stress Management Intervention Program (RASMUS) compared with yoga on stress perception, coping strategies, depressive symptoms, anxiety, resilience and quality of life in people diagnosed with major depressive disorder (MDD) in the short and long term.Read full original descriptionShow less
The Impact of Stress Management Interventions on Stress Perception, Coping Strategies, and Residual Symptoms in Depression: a Randomized Controlled Trial Investigating Psychological, Biological, Epigenetic, and Brain Correlates
The aim of this clinical trial is to evaluate the effects of a Resilience and Stress Management Intervention Program (RASMUS) compared with yoga on stress perception, coping strategies, depressive symptoms, anxiety, resilience and quality of life in people diagnosed with major depressive disorder (MDD) in the short and long term.
In addition to psychological factors, biological parameters will be examined to define biomarkers involved in stress response. In the optional neuroimaging part, the effects of the planned interventions on the structure, metabolism and function of the brain will be investigated. The epigenetic part, which is also optional, will examine the effects of the planned interventions on the histone modifications.
Inclusion: Confirmed diagnosis of MDD,; Outpatient care for at least 3 months,; Ongoing psychopharmacological treatment,; Age between 18 and 65 years,; Knowledge of written and spoken German,; MADRS score ≤ 34 (moderate severity of symptoms),; Written informed consent.
Exclusion: MRI contraindications (claustrophobia, metallic, electrical, magnetic or mechanically driven implants, tattoos on the head or neck or other clinically relevant contraindications); Positive drug urine test; Other Axis I psychiatric disorder (organic mental disorders, psychoactive substance use [excl. caffeine and nicotine abuse], schizophrenia, bipolar disorder, neurotic disorders [excl. anxiety disorders], eating disorders, acute suicidality); Severe somatic illnesses,; History of neurological trauma or trauma to the central nervous system,; Pregnancy/breastfeeding,; Undertaking regular yoga practice (more than once per week) over the past 3 months,; Current use of psychotherapy; Further exclusion criteria for the neuroimaging sub-study:.