Frontlight ResearchEarly access
TerminatedNo phase
GT201 Injection in Combination With Teraplizumab Injection for Treatment of Patients With Non-small Cell Lung Cancer
Key facts
- Who runs it
- Grit Biotechnology
- Where
- China3 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Terminated
- People taking part
- 2 people enrolled
- Started
- 2 Feb 2024
- Ended
- 30 Dec 2025
- Type of study
- Interventional
- Treatments tested
- GT201 injection in combination with teraplizumab injection
- Record updated
- 27 April 2026
- Why it stopped
- The study was terminated from a business perspective.
Who can take part
- Age
- 18 years to 70 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- 1. Voluntarily join the study, signed informed consent form,, willing and able to comply with the study protocol
- 2. Age 18 to 70 years old
- 3. Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1
- 4. Expected survival time of ≥ 12 weeks
- 5. Good function of vital organs
- 6. Subjects entering this study due to disease progression must have an imaging record of disease progression before tumor sampling
- 7. At least one measurable target lesion that meets the definition of RECIST v1.1 after tumor sampling
Who cannot take part
- 1.Patients with uncontrollable tumor-related pain as judged by the investigator; participants requiring analgesic medication must already have a stable analgesic regimen at the time of study entry; symptomatic lesions suitable for palliative radiotherapy should be completed prior to study entry
- 4.Those who have received other clinical trial drug treatment within 4 weeks before preconditioning by lymphodepletion,plan to participate in other clinical trial drug treatment during the study
- 2.Known mental illness, alcoholism, drug use or substance abuse
- 5.The investigators determine that other conditions that make the patient not suitable for enrollment
- 3.Pregnant or lactating women; or women who are pregnant, breastfeeding, or planning to become pregnant within 1 year after cell infusion
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
This study is a single arm, open design aimed at evaluating the safety and tolerability of Autologous Tumor-Infiltrating Lymphocyte (GT201 injection ) in combination with teraplizumab injection for treatment of patients with non-small cell lung cancer,while evaluating pharmacokinetic characteristics and efficacy assessment to determine the optimal biological dose (OBD).
The group in the trial
- GT201 treatment groupTreatment being tested
Treatment: GT201 injection in combination with teraplizumab injection
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Single-arm Clinical Study of Autologous Tumor-Infiltrating Lymphocyte (GT201 Injection ) in Combination With Teraplizumab Injection for Treatment of Patients With Non-small Cell Lung Cancer
- Record updated
- 27 April 2026