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Brain rhythms during movement in Parkinson disease and epilepsy

Studies brain electrical activity during a simple movement task in Parkinson disease or epilepsy.

Key facts

Who runs it
University Hospital, Bordeaux
Where
Bordeaux, FranceSee the site
Trial code
Registry title
Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement
Status
Recruiting
People taking part
30 people, planned
Started
5 Feb 2024
Expected to end
5 Feb 2027
Type of study
Interventional, 2 groups
Treatments tested
  • High Resolution Electroencephalogram (EEG-HR)
  • Stereo-electro-encephalography (SEEG)
Record updated
23 July 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with Parkinson's disease who already have deep brain electrodes, or adults with drug-resistant epilepsy having a pre-surgery brain recording.

Age
18 to 75 years
Sex
All sexes
Disease stage
Parkinson's disease already operated, with electrodes in the subthalamic nucleus connected to a PERCEPT device. Or drug-resistant epilepsy having a phase II pre-surgical assessment with stereo-EEG, with at least one electrode in the basal ganglia or the thalamus.
Earlier treatment
People with Parkinson's disease must already have had the electrode operation.

Main reasons for not taking part

  • Cannot give consent personally
  • Under a legal protection measure or judicial protection
  • Pregnant or breastfeeding
  • Serious or decompensated physical or psychiatric illness

The registry criteria, word for word

Show all 13 criteriaShow less

Who can take part

  • Male or Female
  • Between 18 and 75 years of age
  • With Parkinson's disease and already operated with implantation of electrodes in the Subthalamic nucleus connected to a PERCEPT (TM) device
  • Giving free, informed, written consent signed by the participant and the investigator Or
  • With drug-resistant epilepsy and benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG
  • With at least one electrode exploring the basal ganglia or the thalamus
  • Able to perform the simple motor task
  • Affiliated or beneficiary of a social security scheme
  • Giving free, informed, written consent signed by the participant and the investigator

Who cannot take part

  • Present a serious and/or decompensated somatic or psychiatric illness
  • Be incapable of giving consent personally
  • Be subject to a legal protection measure or be placed under judicial protection
  • Being pregnant or breastfeeding

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 75 years old?

Where in France

  • CHU de BordeauxBordeaux, FranceContact: Jérôme AupyTaking people

About the trial

What the trial wants to find out

The expression of hypokinetic and hyperkinetic motor symptoms is accompanied by pathological synchronous oscillations of neuronal activity in this cortico-subcortical network with a wide frequency range.

Read full original descriptionShow less

The purpose of this research is to study cortico-subcortical oscillations and their synchronization in two pathologies emblematic of hypokinetic (Parkinson's disease) and hyperkinetic (epilepsies) phenomena using a simple motor task and comparing different situations.

The 2 groups in the trial

  • EpilepsyTreatment being tested

    Treatment: Stereo-electro-encephalography (SEEG)

  • parkinson diseaseTreatment being tested

    Treatment: High Resolution Electroencephalogram (EEG-HR)

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement
Plain-language title
Brain rhythms during movement in Parkinson disease and epilepsyGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT06241924, who can take part
Record updated
23 July 2025