Menstrual blood tests to find signs of endometriosis
Studies menstrual blood from women with and without endometriosis, before and after surgery.
Plain-language title generated from the registry record
Registry title: Diagnostic and Prognostic Markers of Endometriosis in Menstrual Blood
Key facts
- Where
- Paris, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT06245512, who can take part
Where in France
- Hôpital CochinParis, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Institut National de la Santé Et de la Recherche Médicale, France
- Trial code
- NCT06245512
- Record updated
- 16 April 2026
- Original description
The goal of this observational study is to identify diagnostic and prognostic biomarkers for endometriosis using menstrual blood, an easily accessible yet overlooked biological fluid in women of reproductive age, affected or not by endometriosisRead full original descriptionShow less
RECHERCHE DE MARQUEURS DIAGNOSTIQUES ET PRONOSTIQUES DE L'ENDOMETRIOSE DANS LE SANG DES REGLES CHEZ LES FEMMES EN AGE DE PROCREER
The goal of this observational study is to identify diagnostic and prognostic biomarkers for endometriosis using menstrual blood, an easily accessible yet overlooked biological fluid in women of reproductive age, affected or not by endometriosis
The main questions it aims to answer are:
* are there relevant differences in the menstrual blood of women affected by endometriosis compared to women without endometriosis? * do some of these differences disappear or lessen when the disease is treated by surgery? Participants will answer questions relevant to endometriosis and provide menstrual blood 1 to 3 times (self-collected with a menstrual cup). A subgroup of participants affected by endometriosis that will undergo surgery for their regular care will provide menstrual blood before and after their surgery.
Researchers will compare the menstrual blood of women with and without endometriosis, and before and after surgery to see if they can identify significant differences.
Inclusion: For all participants:; Women 18-45 of age who; Have their period; Have given their written consent; Have already used a menstrual cup as a method of hygienic protection; Residing or working in Ile de France (Paris Metropolitan area, France); For participants with endometriosis:; diagnosis of endometriosis established by surgery or imaging (ultrasound and/or MRI); presence of one or more painful symptoms > 3 on a visual scale (dysmenorrhea and/or dyspareunia and/or chronic pelvic pain) and/or infertility; for the surgery subgroup: planned surgery in the next 3 months; For participants without endometriosis:; painful symptoms < or equal to 3 on a visual scale (for dysmenorrhea and dyspareunia and chronic pelvic pain),; absence of intense period pain in adolescence (leading to taking pills to control this pain and/or peri-menstrual school absenteeism).
Exclusion: endometriosis surgery within the last 3 months; Autoimmune diseases; Chronic diseases other than endometriosis (diabetes, hypertension); Infectious diseases (HIV, HBV, if known); History of menstrual toxic shock syndrome; For patients with endometriosis:; For all participants:; A person who is the subject of a judicial safeguard measure (by declaration).