Robotic Versus Open Surgery for Gallbladder Cancer
Compares robotic-assisted and open surgery to remove the gallbladder in adults with gallbladder cancer.
Plain-language title generated from the registry record
Registry title: Robotic-assisted Contra Open Resection for Suspected or Confirmed Gallbladder Cancer (ROBOCOP)
Key facts
- Where
- Stockholm, SwedenSee the site
Where in Sweden
- Region StockholmStockholm, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Karolinska University Hospital
- Trial code
- NCT06246448
- Record updated
- 5 September 2025
- Original description
The Robocop trial is an international multi-centre, single blinded, randomized controlled superiority trial conducted in centres experienced in robotic-assisted liver surgery. Eligible patients for radical cholecystectomy will be randomized in a 1:1 ratio to undergo robotic-assisted or open resection within an enhanced recovery setting.Read full original descriptionShow less
Robotic-assisted Contra Open Resection for Suspected or Confirmed Gallbladder Cancer - An International, Multi-centre, Single Blinded, Randomized Controlled Superiority Trial
The Robocop trial is an international multi-centre, single blinded, randomized controlled superiority trial conducted in centres experienced in robotic-assisted liver surgery. Eligible patients for radical cholecystectomy will be randomized in a 1:1 ratio to undergo robotic-assisted or open resection within an enhanced recovery setting.
The primary endpoint is time to functional recovery. Secondary endpoints include length of hospital stay, resection margin, number of retrieved lymph nodes, postoperative complications, quality of life, abdominal wall complaints and direct and indirect costs.
Inclusion: Patient with radiologically suspected or confirmed (≥T1b) incidental gallbladder cancer after cholecystectomy with an indication of radical cholecystectomy, without the need for resection of extrahepatic bile ducts, as decided at a multidisciplinary team conference; Patient sufficiently fit to undergo radical cholecystectomy according to surgeon and anaesthesiologist.
Exclusion: Previous extensive surgery in the upper abdomen (for example open liver surgery); Intraoperative findings of the need to perform resection of extrahepatic bile ducts (patient is then excluded after randomization); Pregnancy; Intraoperative findings of dissemination (patient is then excluded after randomization); Intraoperative findings leading to a simple cholecystectomy only (patient is then excluded after randomization).