Comparing two heart procedures for persistent atrial fibrillation in adults
Compares radiofrequency and cryoablation of the heart's left atrium in people with persistent atrial fibrillation.
Plain-language title generated from the registry record
Registry title: Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Key facts
- Where
- Moscow, RussiaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06253000, who can take part
Where in Russia
- Bakulev National Medical Research Center for Cardiovascular SurgeryMoscow, RussiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Bakulev Scientific Center of Cardiovascular Surgery
- Trial code
- NCT06253000
- Record updated
- 20 July 2026
- Original description
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times. Ischemic stroke in patients with AF is often fatal and, compared with stroke of other etiology, leads to the most pronounced disability and more often recurs. Accordingly, the risk of death in patients with AF-related stroke is 2 times higher, and treatment costs increase 1.5 times.Read full original descriptionShow less
Comparative Analysis of Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium in Patients With Persistent Atrial Fibrillation
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times. Ischemic stroke in patients with AF is often fatal and, compared with stroke of other etiology, leads to the most pronounced disability and more often recurs. Accordingly, the risk of death in patients with AF-related stroke is 2 times higher, and treatment costs increase 1.5 times.
The main interventional method of treating AF, available in most medical institutions, is the use of radio frequency and/or cryoenergy to eliminate destructive damage to the left atrium (LA).
The aim of this study is to compare two different interventional methods and identify predictors of recurrence in patients with persistent and long-term AF.
Inclusion: Age over 18 years old; Atrial fibrillation resistant to antiarrhythmic therapy; Persistent and long-persisting form of atrial fibrillation; The patient's consent to participate in the study.
Exclusion: Previous "open" cardiac surgery; The presence of another cardiac pathology requiring surgical treatment; Congenital heart defects; Bone marrow diseases; Drug-resistant hypertension (despite hypotensive therapy); The left ventricular ejection fraction is less than 40%; Moderate to severe renal insufficiency (creatinine clearance <50 ml/min); Age under 18 and over 80 years old; Pathology of the blood coagulation system; Organically altered mitral valve; There are reasons to assume that the patient will not show up for subsequent visits (control points of the study) for various reasons; The patient's participation in another clinical trial.