Comparing non-radioactive tests of kidney filtration in chronic kidney disease
Compares a non-radioactive kidney filtration test with radioactive tests in adults with kidney disease.
Plain-language title generated from the registry record
Registry title: method VALIDation and evaluation of non-radioactive methods to
measure Glomerular Filtration Rate
Key facts
- Where
- Groningen, NetherlandsSee the site
- Phase
- Phase 4
Where in Netherlands
- Universitair Medisch Centrum GroningenGroningen, NetherlandsTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universitair Medisch Centrum Groningen
- Trial code
- NCT06259422EU 2023-509156-34-02
- Record updated
- 31 December 2025
- Original description
To determine the equivalence of mGFR using 125I-iothalamate and 131I-hippuran versus iohexolRead full original descriptionShow less
VALIDGFR; method VALIDation and evaluation of non-radioactive methods to measure Glomerular Filtration Rate
To determine the equivalence of mGFR using 125I-iothalamate and 131I-hippuran versus iohexol
Inclusion: Scheduled to undergo a kidney function measurement test as part of standard care; Age ≥ 18 years; Written informed consent.
Exclusion: History of hypersensitivity to iodinated contrast media or one of the excipients in the formulation of iohexol (trometamol, sodium calcium edetate, hydrochloric acid); Subjects with (suspected or known) thyrotoxicosis; Pregnant women and women of child-bearing potential who are not using reliable contraception; Patients who are unlikely to comply to the trial’s procedure (non-compliance).