Studies genes and sleep apnea in people with diabetes and obesity in Greenland
Looks at genes, diabetes and sleep apnea in adults with diabetes and severe obesity.
Plain-language title generated from the registry record
Registry title: Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
Key facts
- Where
- Nuuk, GreenlandSee the site
Where in Greenland
- Steno Diabetes Center Greenland, Queen Ingrids HospitalNuuk, GreenlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Steno Diabetes Center Greenland
- Trial code
- NCT06264427
- Record updated
- 20 February 2024
- Original description
The goal of this clinical trial is to perform a detailed description of the feno- and genotype of people living with type 2 diabetes and severe obesity who are linked to care at Steno Diabetes Center Greenland.Read full original descriptionShow less
Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
The goal of this clinical trial is to perform a detailed description of the feno- and genotype of people living with type 2 diabetes and severe obesity who are linked to care at Steno Diabetes Center Greenland.
The main questions it aims to answer are:
* Are monogenetic diabetes variants associated with the same risk of developing late diabetic complications as other types of diabetes? * Can genotyping and thereby personalized medicine be implemented in Greenland, and can personalized medicine lead to improved treatment? * What is the prevalence of sleep apnea among high-risk individuals in Greenland? * Is it possible to develop and implement a simple algorithm for the identification of sleep apnea in Greenland that can ensure treatment of severe sleep apnea?
Participants will:
* Answer WHO-5 and FOSQ-10 questionnaires regarding quality of life and functional outcomes of sleepiness * Perform VAGUS examinations for Cardiovasculare Autonomic Neuropathy * Clinical examination of height, weight, circumference of hip, waist and neck, Friedman tonsil and tongue score, nasal air flow, nasal septal deviation * Blood samples for full genome sequencing
Inclusion: Type 2 diabetes and/or morbid obesity (BMI >40); Over 18 years old.
Exclusion: Does not speak either English, Danish or Greenlandic.