Studies genes and sleep apnea in people with diabetes and obesity in Greenland
Looks at genes, diabetes and sleep apnea in adults with diabetes and severe obesity.
Key facts
- Who runs it
- Steno Diabetes Center Greenland
- Where
- Nuuk, GreenlandSee the site
- Trial code
- Registry title
- Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- 15 Jul 2022
- Expected to end
- 31 Dec 2026
- Type of study
- Interventional
- Treatments tested
- Whole genome sequencing
- VAGUS
- NightOwl
- CPAP
- Record updated
- 20 February 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults in Greenland who have type 2 diabetes and/or severe obesity and are linked to care at Steno Diabetes Center Greenland.
- Age
- Over 18 years old
- Sex
- All sexes can join.
- Disease stage
- Type 2 diabetes and/or morbid obesity (BMI >40).
Main reasons for not taking part
- Does not speak English, Danish or Greenlandic
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- Type 2 diabetes and/or morbid obesity (BMI >40)
- Over 18 years old
Who cannot take part
- Does not speak either English, Danish or Greenlandic
Where in Greenland
- Steno Diabetes Center Greenland, Queen Ingrids HospitalNuuk, GreenlandContact: Mads Mose Jensen, MD.Taking people
About the trial
What the trial wants to find out
The goal of this clinical trial is to perform a detailed description of the feno- and genotype of people living with type 2 diabetes and severe obesity who are linked to care at Steno Diabetes Center Greenland.
Read full original descriptionShow less
The main questions it aims to answer are:
* Are monogenetic diabetes variants associated with the same risk of developing late diabetic complications as other types of diabetes? * Can genotyping and thereby personalized medicine be implemented in Greenland, and can personalized medicine lead to improved treatment? * What is the prevalence of sleep apnea among high-risk individuals in Greenland? * Is it possible to develop and implement a simple algorithm for the identification of sleep apnea in Greenland that can ensure treatment of severe sleep apnea?
Participants will:
* Answer WHO-5 and FOSQ-10 questionnaires regarding quality of life and functional outcomes of sleepiness * Perform VAGUS examinations for Cardiovasculare Autonomic Neuropathy * Clinical examination of height, weight, circumference of hip, waist and neck, Friedman tonsil and tongue score, nasal air flow, nasal septal deviation * Blood samples for full genome sequencing
The group in the trial
- Intervention armTreatment being tested
All participants will undergo examination for genom sequencing, diabetic complications and obstructive sleep apnea. Treatment for these conditions will not be randomized, but will be offered any participant who fulfills the excision treatment criteria
Treatment: Whole genome sequencing, VAGUS, NightOwl, and CPAP
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
- Plain-language title
- Studies genes and sleep apnea in people with diabetes and obesity in GreenlandGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 20 February 2024