Studies whether gut and body bacteria are linked to endometriosis
Compares bacteria in body samples from women with endometriosis and others.
Plain-language title generated from the registry record
Registry title: A Study on the Correlation Between Endometriosis and Intra-tissue Microbiota
Key facts
- Where
- Guangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 18-52 who are having laparoscopic surgery and have regular periods. It studies how endometriosis relates to the microbes living in body tissue.
- Age
- 18 to 52 years
- Sex
- Women only
- Earlier treatment
- No antibiotics or probiotics, by mouth or on the skin or in the vagina, in the 6 months before surgery.
Main reasons for not taking part
- Pregnancy
- Cancer or borderline disease found during surgery or in tissue tests
- Immune problems, allergies or autoimmune disease
- Past gene therapy, blood transfusion, stem cell therapy or bone marrow transplant
- History of pelvic inflammatory disease
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 52 years old?
Source: NCT06266897, who can take part
Where in China
- Zhujiang HospitalGuangzhou, ChinaContact: Ying MaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Zhujiang Hospital
- Trial code
- NCT06266897
- Record updated
- 20 February 2024
- Original description
Endometriosis (EM) is a common gynecological condition, but the pathogenesis of it has not yet been clarified. Here, the investigators wanted to investigate the correlation between endometriosis and the intra-tissue microbiota. The investigators planed to collect serum, vaginal swabs, cervical mucus, feces, peritoneal fluid, and endometrial tissue for sequencing and experiments.Read full original descriptionShow less
A Study on the Correlation Between Endometriosis and Intra-tissue Microbiota
Endometriosis (EM) is a common gynecological condition, but the pathogenesis of it has not yet been clarified. Here, the investigators wanted to investigate the correlation between endometriosis and the intra-tissue microbiota. The investigators planed to collect serum, vaginal swabs, cervical mucus, feces, peritoneal fluid, and endometrial tissue for sequencing and experiments.
Inclusion: Women aged 18-52 years old; Regular menstruation with a cycle of 28-35 days; No sexual intercourse 1 week before the operation; No systemic or local use of antibiotics and probiotics for 6 months prior to surgery; No history of acute or chronic pelvic inflammatory disease; Subjects fully understand the significance of the study and sign the informed consent form.
Exclusion: Absolute or relative contraindications to laparoscopic or hysteroscopic surgery; Intraoperative conditions or pathological examination suggest a malignant or junctional disease; History of gene therapy, blood transfusion, stem cell therapy, or bone marrow transplantation; Psychiatric, personality disorders, or abuse of psychoactive substances; Immunodeficiencies, allergies, or autoimmune diseases; In pregnancy; Severe anatomical abnormalities of the pelvis; Pelvic contamination with large amounts of blood during laparoscopic operation; Contraindications to endotracheal intubation anesthesia.