Studies whether gut and body bacteria are linked to endometriosis
Compares bacteria in body samples from women with endometriosis and others.
Plain-language title generated from the registry record
Registry title: A Study on the Correlation Between Endometriosis and Intra-tissue Microbiota
Key facts
- Where
- Guangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 52 years old?
Source: NCT06266897, who can take part
Where in China
- Zhujiang HospitalGuangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Zhujiang Hospital
- Trial code
- NCT06266897
- Record updated
- 20 February 2024
- Original description
Endometriosis (EM) is a common gynecological condition, but the pathogenesis of it has not yet been clarified. Here, the investigators wanted to investigate the correlation between endometriosis and the intra-tissue microbiota. The investigators planed to collect serum, vaginal swabs, cervical mucus, feces, peritoneal fluid, and endometrial tissue for sequencing and experiments.Read full original descriptionShow less
A Study on the Correlation Between Endometriosis and Intra-tissue Microbiota
Endometriosis (EM) is a common gynecological condition, but the pathogenesis of it has not yet been clarified. Here, the investigators wanted to investigate the correlation between endometriosis and the intra-tissue microbiota. The investigators planed to collect serum, vaginal swabs, cervical mucus, feces, peritoneal fluid, and endometrial tissue for sequencing and experiments.
Inclusion: Women aged 18-52 years old; Regular menstruation with a cycle of 28-35 days; No sexual intercourse 1 week before the operation; No systemic or local use of antibiotics and probiotics for 6 months prior to surgery; No history of acute or chronic pelvic inflammatory disease; Subjects fully understand the significance of the study and sign the informed consent form.
Exclusion: Absolute or relative contraindications to laparoscopic or hysteroscopic surgery; Intraoperative conditions or pathological examination suggest a malignant or junctional disease; History of gene therapy, blood transfusion, stem cell therapy, or bone marrow transplantation; Psychiatric, personality disorders, or abuse of psychoactive substances; Immunodeficiencies, allergies, or autoimmune diseases; In pregnancy; Severe anatomical abnormalities of the pelvis; Pelvic contamination with large amounts of blood during laparoscopic operation; Contraindications to endotracheal intubation anesthesia.