Using ROSA for Challenging The TKA Standard of Care
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 80 years old?
Source: NCT06267482, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Trial code
- NCT06267482
- Record updated
- 21 September 2026
- Original description
This is a prospective, randomized controlled trial using the cruciate retaining, MC Persona to comparing the conventional TKA to ROSA assisted TKA. Patients will be randomized to one of three study trial arms.Read full original descriptionShow less
Challenging The TKA Standard Of Care: Patient Specific Surgical Targets As Enabled By The Rosa
This is a prospective, randomized controlled trial using the cruciate retaining, MC Persona to comparing the conventional TKA to ROSA assisted TKA. Patients will be randomized to one of three study trial arms.
1. Standard of care medial parapetallar approach (Control) 2. ROSA PSA medial parapetallar approach 3. ROSA PSA medial subvastus approach Participants will be followed for 1 year post surgery with a combination of perioperative parameters, imaging, patient reported outcomes, functional outcomes, blood and tissue sampling for inflammatory information and activity levels.
Inclusion: Symptomatic osteoarthritis of the knee indicating primary total knee arthroplasty; Varus knee deformity of 0 to 10 degrees; Sufficient ligamentous function to warrant retention of the posterior cruciate ligament; Between the ages of 21 and 80 inclusive; Patients willing and able to comply with follow-up requirements and self-evaluations; Ability to give informed consent.
Exclusion: Active or prior infection; Prior trauma to the tibia or femur resulting in malalignment, canal occlusion, or open reduction and internal fixation; Bone defects requiring augments, cones and/or stemmed implants; Intraoperative findings of insufficient contact between the implant and the bone surface; Medical condition precluding major surgery; Neurologic condition limiting mobility; Predominantly inflammatory arthropathy; Patellectomy; PCL deficiency; Major coronal plane deformity; Valgus alignment; Body Mass Index of 40 or more.