Studies body changes in people with obesity before and after bariatric surgery
Observes body changes in adults with obesity before and after weight-loss surgery.
Plain-language title generated from the registry record
Registry title: Surgical-imaging Research on Obesity (SIRO)
Key facts
- Where
- Xuzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06268262, who can take part
Where in China
- Affiliated Hospital of Xuzhou Medical UniversityXuzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The Affiliated Hospital of Xuzhou Medical University
- Trial code
- NCT06268262
- Record updated
- 15 March 2024
- Original description
The global obesity epidemic is well established, and is an important public health issue. The previous researches had applied the clues that obesity is a kind of systemic disease. The investigators hypothesized that a serious alteration of the body systems will occur after bariatric surgery, which may shed light on the mechanisms of obesity. Thus, the research aims to combine the imaging and surgery to investigate the alterations of the body that induced by obese and alterations after surgery.Read full original descriptionShow less
Surgical-imaging Combined Research on Obesity
The global obesity epidemic is well established, and is an important public health issue. The previous researches had applied the clues that obesity is a kind of systemic disease. The investigators hypothesized that a serious alteration of the body systems will occur after bariatric surgery, which may shed light on the mechanisms of obesity. Thus, the research aims to combine the imaging and surgery to investigate the alterations of the body that induced by obese and alterations after surgery.
Inclusion: Meeting the obesity criteria (BMI > 28); 2) Meeting the indications for bariatric surgery, planning to undergo surgery for the first time; 3) Age between 18-65 years old, no gender restrictions; 4) Right-handed, of Han ethnicity; 5) Informed consent to the study, willing to cooperate with the research, and able to sign an informed consent form; Healthy volunteers with a BMI between 18.5-23.9; Age between 18-65 years old, no gender restrictions; Right-handed, of Han ethnicity; Informed consent to the study, willing to cooperate with the research, and able to sign an informed consent form.
Exclusion: Unable to undergo surgery as planned; Alcohol or drug dependence; Contraindications for MR scanning (pacemakers, cochlear implants, metal objects in the body, claustrophobia, weight exceeding the machine's load limit, etc.); Use of drugs affecting the nervous system or psychotropic drugs within the last six months; Secondary obesity caused by other organic diseases or medication (such as hormone use, etc.); Eating disorders; Meeting the criteria for organic mental disorders, severe mental disorders (schizophrenia, etc.), or other serious mental illnesses requiring clinical intervention; History of neurological organic diseases (brain tumors, epilepsy, cerebrovascular accidents, severe head trauma, etc.); History of congenital heart disease (myocardial infarction, severe arrhythmias, heart failure, cardiomyopathy, rheumatic heart disease, congenital heart disease, etc.); Severe liver, kidney, lung, digestive dysfunction, endocrine, and blood system diseases; Active infections within the last two weeks (fever, upper respiratory infection, acute gastroenteritis, etc.); Pregnant or breastfeeding; Low cognitive ability and incapable of cooperating with the study; The same criteria as points 3) to 13) above.