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CompletedNo phase

TMS for Veterans Attending a 2-week Intensive Outpatient Program for PTSD

Key facts

Who runs it
Rush University Medical Center
Where
Chicago, United StatesSee the site
Trial code
Status
Completed
People taking part
6 people enrolled
Started
11 Jan 2022
Ended
27 Oct 2025
Type of study
Interventional
Treatments tested
  • TMS
Record updated
20 February 2026

Who can take part

Age
18 years to 65 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Veterans or service members between the ages of 18 and 65 who are attending the 2- week Intensive Outpatient Program at the Road Home Program and have not had significant PTSD symptom change based on the PCL-5 during the first week of treatment
  • Participants with an HDRS-21 score ≤ 26 at screening visit

Who cannot take part

  • Individuals with implants and non-removable metals which prevent them from safely receiving TMS, including:; Aneurysm clips or coils; Stents in the head, neck, or brain; Deep brain stimulators; Metallic implants in the head, neck, or brain (braces and dental implants do not interfere and are safe for TMS); Shrapnel or bullet fragments in or near the head; Facial tattoos with metallic or magnetic-sensitive ink; Other metal devices or ferromagnetic objects implanted in or near the head; Pacemakers, intra-cardiac lines, or implanted medical pumps
  • Individuals currently on Benzodiazepine at a dose higher than 3mg or Lorazepam or equivalent
  • Individuals with previous TMS treatment
  • Individuals with a history of seizures or epilepsy (except those therapeutically induced by ECT)
  • Individuals diagnosed with major, chronic mental health illnesses such as Psychotic Disorders, Bipolar Disorders, and Obsessive Compulsive Disorder
  • Individuals with a history of substance abuse within the past six months
  • Individuals with significant neurological disorders such as Parkinson's disease, Huntington's chorea, and Multiple sclerosis
  • Individuals with unstable physical disease, such as unstable cardiac diseases
  • Women who are breastfeeding or pregnant

Where in United States

  • Rush University Medical CenterChicago, United States

About the trial

What the trial wants to find out

The goal of this study is to determine whether complementing regular intensive PTSD treatment with intermittent theta burst stimulation (iTBS) applied to the right dorsolateral prefrontal cortex (DLPFC) can improve treatment response for individuals attending a 2-week intensive outpatient program (IOP) for PTSD.

The group in the trial

  • TMSTreatment being tested

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Intensive PTSD Treatment Combined With Transcranial Magnetic Stimulation: A Pilot Study
Record updated
20 February 2026