Eye scan imaging to track advanced glaucoma over 3 years
Studies OCT angiography eye scans in adults with advanced glaucoma, followed 3 years.
Plain-language title generated from the registry record
Registry title: Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
Key facts
- Where
- Nantes, FranceSee the 2 sites
Where in France
- CHU NantesNantes, FranceTaking people
- Jean-Baptiste DucloyerNantes, FranceNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Nantes University Hospital
- Trial code
- NCT06274593
- Record updated
- 24 June 2026
- Original description
Glaucoma is a chronic disease of the optic nerve, characterized by progressive loss of nerve cells in the retina, leading to progressive loss of peripheral and central vision. There are in fact several types of glaucoma, which is the world's second leading cause of blindness after cataracts, and the leading cause of irreversible blindness.Read full original descriptionShow less
Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
Glaucoma is a chronic disease of the optic nerve, characterized by progressive loss of nerve cells in the retina, leading to progressive loss of peripheral and central vision. There are in fact several types of glaucoma, which is the world's second leading cause of blindness after cataracts, and the leading cause of irreversible blindness.
To date, to our knowledge, there is no work analyzing the progression of angiographic OCT in patients with glaucoma.
The main aim of this study is to compare the 3-year progression rate of 3 examinations in advanced glaucoma patients: one functional (visual field) and two anatomical (OCTa and OCTrnfl).
Inclusion: Men and women aged 18 and over; Patient with glaucoma followed in the ophthalmology department of Nantes University Hospital; mean visual field deficit (MD) >10dB.
Exclusion: Retinal vascular pathology (moderate to severe non-proliferative diabetic retinopathy, complicated diabetic retinopathy, OVCR/OBVR, OACR/OBAR, NOIAA...) Non-glaucomatous optic neuropathy, neurological pathology leading to visual field deficit (stroke with HLH, quadranopsia, chiasmatic Sd...); Retinal pathology leading to visual field impairment (e.g. retinitis pigmentosa); Significant environmental disorders impairing retinal imaging (e.g. active uveitis, dense cataract); PPR (retinal PanPhotocoagulation), retinal cerclage; AMD and other macular pathologies that can lead to central visual field deficits; Loss of fixation point preventing visual field formation Pregnant or breast-feeding women; Protected adults under guardianship or curatorship; with unreliable visual fields (false positives and false negatives > 33%); with an uninterpretable OCTrnfl or OCTa (artifact, low quality score).