CompletedPhase 3
Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism
Key facts
- Who runs it
- King Edward Medical University
- Where
- Pakistan1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- Phase
- Phase 3
- People taking part
- 62 people enrolled
- Started
- 1 Mar 2024
- Ended
- 1 Jan 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Vitamin D
- Levothyroxin
- Record updated
- 11 March 2025
Who can take part
- Age
- 12 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Patients of all genders
- Age more than 12 years
- Biochemically hypothyroid (overt \& subclinical)
- Vitamin D level between 10-70ng/ml
- TC <250mg/dl, LDL 70-144mg/dl, TGs 150-499mg/dl
Who cannot take part
- Patient taking lipid lowering drugs
- Known Atherosclerotic Cardiovascular Disease
- History of Alcoholism (>14 units/day)
- History of Beta blocker intake
- BMI>35kg/m2
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The goal of this clinical trial is to study the improvement of lipid levels in hypothyroid individuals after staring treatment.
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The main question it aims to answer is:
• whether adding Vitamin D to standard therapy has any additional benefits
Participants will be given Vitamin D in replacement doses according to their pre-existing Vitamin D level in addition to levothyroxine.
Researchers will compare them with another group receiving only levothyroxine to see how much lipids improve in them
The 2 groups in the trial
- Vitamin D + LevothyroxineTreatment being tested
Treatment: Vitamin D and Levothyroxin
- Levothyroxine AloneExisting treatment, for comparison
Treatment: Levothyroxin
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- To Compare the Effectiveness of Vitamin D & Levothyroxine Combination Therapy and Levothyroxine Alone on Serum Lipid Profile in Patients With Hypothyroidism
- Record updated
- 11 March 2025