Collects blood and other samples from people with heart failure to study
Collects blood and other samples from adults with heart failure to study how it develops.
Plain-language title generated from the registry record
Registry title: Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)
Key facts
- Where
- Baltimore and Falls Church, United StatesSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 100 years old?
Source: NCT06280820, who can take part
Where in United States
- University of Maryland School of MedicineBaltimore, United StatesNo longer taking part
- Inova Fairfax HospitalFalls Church, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Heart, Lung, and Blood Institute (NHLBI)
- Trial code
- NCT06280820
- Record updated
- 10 November 2026
- Original description
Background:Read full original descriptionShow less
Multi-scale Phenotyping of Heart Failure: From Precision Phenotyping to Population Inference (PHENO-HEART)
Background:
More than 6.5 million people in the United States live with heart failure (HF), and more than a million new cases are diagnosed each year. Treatments have improved in recent years, but researchers want to understand more about how HF develops. To do this, they need to compare blood and other samples from many people with HF.
Objective:
To collect blood and other samples from people with HF. These samples will be used to identify and study proteins and other factors that may lead to decreased heart function over time.
Eligibility:
People aged 18 years and older with heart failure.
Design:
Participants will be asked to join the study based on a review of their medical records.
They will have 1 study visit. They will provide a blood sample: About 3 tablespoons will be collected from a needle inserted into a vein.
Other tests are optional: Participants may provide urine and stool samples. They may have a cotton swab rubbed on the inside of the mouth to collect DNA.
Participants may also take 3 questionnaires. They will answer questions about dietary, social, and other factors that affect their health. Participants will receive compensation.
Researchers will follow the participants health by monitoring their medical records for up to 5 years.
Exclusion: History of ventricular assist device; History of cardiac transplant; An individual who meets any of the following criteria will be excluded from participation in this study:; Living or residing outside of the geographic location designated for the study at the time of enrollment.
INCLUSION CRITERIA:; In order to be eligible to participate in this study, an individual must meet all of the following criteria:; Clinical diagnosis of "active" HF documented by a cardiology provider's note in the medical record. Active HF is the presence of signs or symptoms that are deemed to be related to heart failure, as documented in the participants' medical records; Able and willing to undergo the consent process and provide consent; Willing to comply with required study activities; 18 years of age or older.