Studying Biomarkers Around Colorectal Surgery and Colon Cancer
Tests possible blood and tissue markers in adults having bowel surgery or colon cancer care.
Plain-language title generated from the registry record
Registry title: Colorectal Omics and OfCS Proteoglycans
Key facts
- Where
- Hillerød and Viborg, DenmarkSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who have, or may have, colorectal cancer or another bowel disease and will have planned colon or rectum surgery or stoma closure.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- Colorectal cancer or suspected cancer or adenoma, inflammatory bowel disease, late complications of colon diverticulosis, colostomy reversal, or another diagnosis that needs colorectal surgery.
- Earlier treatment
- People who were already included in this study cannot join.
Main reasons for not taking part
- Surgery at the same time on the liver (removal of metastases is allowed), the whole stomach, or the cardia
- Whipple's procedure or another major pancreas operation (removal of the pancreatic tail is allowed)
- Kidney removal (total or partial) or bladder removal at the same time
- Known pregnancy
- Not living in Denmark
Read by machine on 9 November 2026.
Where in Denmark
- Nordsjaellands HospitalHillerød, DenmarkTaking people
- Regionshospitalet ViborgViborg, DenmarkNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Claus Anders Bertelsen, PhD, MD
- Trial code
- NCT06287671
- Record updated
- 30 December 2024
- Original description
This observational study aims to test proteomics, metabolomics and proteoglycans as predictors of postoperative complications after colorectal surgery and as biomarkers of colorectal cancer.Read full original descriptionShow less
Colorectal OmiCs and Oncofetal Chondroitin Sulfate-modified Proteoglycans
This observational study aims to test proteomics, metabolomics and proteoglycans as predictors of postoperative complications after colorectal surgery and as biomarkers of colorectal cancer.
The main questions to answer are:
* can these biomarkers predict anastomotic leakages * can these biomarkers predict recurrence after colorectal cancer * can these biomarkers be used as diagnostic tests for colorectal cancer * can these biomarkers be identified in the tumor
Participants will undergo elective colorectal resection or stoma closure.
Inclusion: Patients diagnosed or with suspicion of colorectal cancer or adenoma, inflammatory bowel disease, late complications to colon diverticulosis, colostomy reversal or other diagnoses requiring colorectal resection; Patients planned to undergo elective surgical procedures coded as KJFB20-KJFB99, KJFG30-37 or KJGB00-97 according to the Danish modification of the NOMESCO Classification of Surgical Procedures; Able to speak Danish, English, or other languages where professional interpretation is available; Able to give informed consent.
Exclusion: Patients undergoing synchronous: liver resection (patients undergoing metastasectomies can be included); total gastrectomy or cardia resection; Whipple's procedure or another major pancreatic resection (resections of the pancreatic tail can be included); total or partial nephrectomies or cystectomy; Patients previously included in the study; Patients known to be pregnant (pregnancy test not required); Non-resident in Denmark.