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Propolis and royal jelly for inflammation in kidney disease or high blood pressure

Tests propolis with royal jelly in adults with kidney disease or hypertension.

Plain-language title generated from the registry record
Registry title: Green Propolis Extract and Royal Jelly in Hypertensive Patients and/or With Chronic Kidney Disease

Key facts

Where
Rio de Janeiro, BrazilSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with chronic kidney disease and high blood pressure. Some are in CKD stages 3 to 5, and some are on regular hemodialysis.

Age
18 to 75 years
Sex
All sexes can join.
Disease stage
Chronic kidney disease stages 3 and 5 (GFR from 15 to 59 mL/min), or on regular hemodialysis for at least 6 months.
Earlier treatment
Receiving outpatient nutrition treatment for at least 6 months, or regular hemodialysis for at least 6 months. Using one to three blood pressure drugs.

Main reasons for not taking part

  • Autoimmune or infectious diseases, diabetes, cancer or AIDS
  • Pregnant women
  • Using antibiotics, catabolic drugs, or antioxidant vitamin supplements, prebiotics or probiotics
  • Hemodialysis through a catheter
  • Allergy to corn starch or bee stings, or a recent heart attack or stroke

Read by machine on 9 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 75 years old?

Source: NCT06288204, who can take part

Where in Brazil

  • Denise mafraRio de Janeiro, BrazilTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Universidade Federal Fluminense
Trial code
NCT06288204
Record updated
15 May 2026
Original description
This work aims to evaluate the effects of the association of green propolis extract with royal jelly on inflammation and oxidative stress in participants with chronic kidney diseases (CKD) and Systemic arterial hypertension (SAH), in a longitudinal, randomized, double-blind, placebo-controlled clinical trial that will be carried out for 2 months.Read full original descriptionShow less

Association of Green Propolis Extract and Royal Jelly to Modulate Inflammation and Oxidative Stress in Hypertensive Patients and/or With Chronic Kidney Disease

This work aims to evaluate the effects of the association of green propolis extract with royal jelly on inflammation and oxidative stress in participants with chronic kidney diseases (CKD) and Systemic arterial hypertension (SAH), in a longitudinal, randomized, double-blind, placebo-controlled clinical trial that will be carried out for 2 months.

Inclusion: patients in stages 3 and 5 of CKD (GFR from 15 to 59 mL/min),; patients receiving ambulatorial nutrition treatment at least 6 months; patients on regular Hemodialysis treatment for at least 6 months; patients using one to three antihypertensive drugs.

Exclusion: patients using catabolic drugs or antibiotics; autoimmune and infectious diseases,; diabetes; cancer; Patients on regular intake of propolis who are allergic to corn starch or report being allergic to bee stings; patients with acute myocardial infarction (AMI) and/or cerebrovascular accident (CVA); AIDS; pregnant women; patients with catheter access to hemodialysis; patients using antioxidant vitamin supplements, prebiotics, probiotics, symbiotic,.

ClinicalTrials.gov NCT06288204