Nerve Transfer to Improve Function in High Level Tetraplegia
Key facts
- Where
- Ann Arbor, Baltimore, Houston, Miami, Philadelphia, Salt Lake City, St Louis, Stanford, and Winston-Salem, United StatesSee the 9 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06288763, who can take part
Where in United States
- University of MichiganAnn Arbor, United StatesContact: Savannah SolomonTaking people
- Johns Hopkins UniversityBaltimore, United StatesContact: Chava RobertsTaking people
- Houston MethodistHouston, United StatesContact: Amber BehneTaking people
- University of MiamiMiami, United StatesContact: George Jimsheleishvili, MDTaking people
- University of PennsylvaniaPhiladelphia, United StatesContact: Leah CoghlanTaking people
- University of UtahSalt Lake City, United StatesContact: Kirstianna LombardiTaking people
- Washington University in St. LouisSt Louis, United StatesContact: Linda KoesterTaking people
- Stanford UniversityStanford, United StatesContact: Anthony BetTaking people
- Wake Forest Medical CenterWinston-Salem, United StatesContact: Wendy JenkinsTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Washington University School of Medicine
- Trial code
- NCT06288763
- Record updated
- 11 March 2026
- Original description
The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.Read full original descriptionShow less
Nerve Transfer to Restore Upper Limb Function and Quality of Life in High Tetraplegia
The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.
Participants will:
* undergo standard of care pre- and post-op testing and study exams * complete pre- and post-questionnaires * undergo standard of care nerve transfer surgeries * follow-up with surgeon at 6/12/18/24/36 and potentially at 48 months * attend therapy at local therapist for up to 2 years postop.
Inclusion: 18-80 years of age; High cervical SCI (motor level C1-C4); Motor complete SCI AIS grade A-B; Plateaued spontaneous recovery for at least 6 months of non-operative therapy; SCI greater than 6 months and fewer than 60 months since injury; At least MRC 4/5 donor strength; Mentally and physically willing and able to comply with evaluations.
Exclusion: Currently undergoing long-term steroid therapy; Active infection at the operative site or systemic infection; Active malignancy; Any return or ongoing recovery of distal motor function; Significant joint contractures and/or limitations in passive range of motion in the arm; Mentally or physically compromised making it impossible to complete study activities; Immunologically suppressed; Pregnancy.