Study of tuberculosis in Italian children and teenagers through observation
Observes children with tuberculosis infection across Italy to better understand the disease in young patients.
Plain-language title generated from the registry record
Registry title: Multicenter Italian Cohort Study on Tuberculosis in Pediatric Age
Key facts
- Where
- Bari, Belluno, Bologna, Florence, Genova, Milan, Modena, Naples, Palermo, Parma, Pavia, Pisa, Prato, Roma, and Torino, ItalySee the 17 sites
Where in Italy
- Ospedale Pediatrico Giovanni XXIIIBari, ItalyTaking people
- Ospedale di BellunoBelluno, ItalyTaking people
- Universita di BolognaBologna, ItalyTaking people
- Meyer Children's Hospital IRCCSFlorence, ItalyTaking people
- IRCCS Istituto Giannina GasliniGenova, ItalyTaking people
- Fondazione IRCCS Cà Granda Ospedale Maggiore PoliclinicoMilan, ItalyTaking people
- Ospedale Luigi SaccoMilan, ItalyTaking people
- Policlinico di ModenaModena, ItalyTaking people
- Università Federico IINaples, ItalyTaking people
- Ospedale dei Bambini "G.Di Cristina"Palermo, ItalyTaking people
- Ospedale di ParmaParma, ItalyTaking people
- IRCCS Policlinico San MatteoPavia, ItalyTaking people
- Azienda Ospedaliero Universitaria PisanaPisa, ItalyTaking people
- Azienda USL Toscana CentroPrato, ItalyTaking people
- IRCCS Ospedale Pediatrico Bambin GesùRoma, ItalyTaking people
- Policlinico Universitario Agostino Gemelli IRCCSRoma, ItalyTaking people
- Ospedale Regina MargheritaTorino, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Meyer Children's Hospital IRCCS
- Trial code
- NCT06289660
- Record updated
- 4 March 2024
- Original description
According to the WHO report of 2021, approximately 10 million new cases were reported in 2020, of which 1 million occurred in the pediatric population. However, epidemiological data available on tuberculosis (TB) in pediatric age are extremely limited due to diagnostic challenges in this patient category. Furthermore, children are almost never included in national surveillance systems due to the lack of connections between individual pediatricians, pediatric hospitals, and national surveillance programs. It is therefore reasonable to assume that the disease may be significantly underestimated both in Italy and worldwide.Read full original descriptionShow less
Multicenter Italian Observational Cohort Study on Tuberculosis in Pediatric Age
According to the WHO report of 2021, approximately 10 million new cases were reported in 2020, of which 1 million occurred in the pediatric population. However, epidemiological data available on tuberculosis (TB) in pediatric age are extremely limited due to diagnostic challenges in this patient category. Furthermore, children are almost never included in national surveillance systems due to the lack of connections between individual pediatricians, pediatric hospitals, and national surveillance programs. It is therefore reasonable to assume that the disease may be significantly underestimated both in Italy and worldwide.
Inclusion: Pediatric patients (0-18 years old) at the time of the initial observation; Patients affected by active and latent TB, as defined by the criteria of the World Health Organization; Patients exposed to TB who are found to be non-infected at the end of the window period; Informed consent signed by parents/legal guardian or by the patient who has reached the legal age of consent, assent of the minor.
Exclusion: None.