Studying Pyrophosphate and Blood Vessel Damage in Children With Kidney Disease
Studies pyrophosphate levels and blood vessel disease in children with chronic kidney disease.
Plain-language title generated from the registry record
Registry title: Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease
Key facts
- Where
- Nice, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 0 and 18 years old?
Source: NCT06300788, who can take part
Where in France
- CHU Nice - Hopital de l Archet 2Nice, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centre Hospitalier Universitaire de Nice
- Trial code
- NCT06300788
- Record updated
- 27 July 2026
- Original description
The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease, with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy.Read full original descriptionShow less
Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease - PPi-DIA
The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease, with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy.
Inclusion: All groups :; Minor patients (<18 years); Patients of both sexes; Informed patients and parents who have signed the informed consent form; Patients affiliated to social security; Control group :; Patients with no particular pathology undergoing surgery and receiving a preoperative check-up; CKD groups :; Patients on dialysis for more than 3 months, regardless of technique; Kidney transplant patients; Patients with CKD, whatever the cause.
Exclusion: Progressive cancer or kidney disease; Treatments that may modify PPi concentration (e.g. bisphosphonates).