Virtual Reality Pain Relief Studied in Children With Burns and Leukemia
Uses brain imaging to study virtual reality pain relief in children during painful procedures.
Key facts
- Who runs it
- Nationwide Children's Hospital
- Where
- Columbus, United StatesSee the site
- Trial code
- Registry title
- VR-PAT and fNIRS to Identify CNS Biomarkers of Pain
- Status
- Not yet recruiting
- People taking part
- 4 people, planned
- Starts
- Jul 2027
- Expected to end
- Dec 2027
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- VR-PAT
- Record updated
- 9 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children and teenagers aged 6 to 17 who are in the hospital for a burn injury and need their dressing changed daily for 3 days. It tests virtual reality for pain relief.
- Age
- 6 to 17 years, including both ends
- Sex
- All sexes can join.
- Disease stage
- Acute burn injury. The child is admitted to the NCH burn unit and has a dressing that needs daily changes over 3 days.
Main reasons for not taking part
- Wounds that may interfere with study procedures
- Vision, hearing, thinking or movement problems that prevent the study measures from being used properly
- History of motion sickness, seizure disorder, dizziness, or migraine headaches triggered by visual auras
- Minors in foster care, prisoners, or people who are currently pregnant
- Suspected child abuse, or unable to communicate in English
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Being treated for acute burn injury
- Age 6-17 years, inclusive
- Admitted to NCH burn unit for treatment
- Have a dressing that requires daily changes over 3 days
- Patient and family caregivers can communicate (read and write) using English
Who cannot take part
- History of motion sickness, seizure disorder, dizziness, or migraine headaches precipitated by visual auras
- Any wounds that may interfere with study procedures
- Vision, hearing, or cognitive/motor impairments preventing valid administration of study measures
- Minors in foster care, prisoners, or currently pregnant
- Suspected child abuse
- Unable to communicate in English
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 17 years old?
Where in United States
- Nationwide Children's HospitalColumbus, United StatesContact: Henry Xiang, MD, MPH, PhD, MBANo longer taking part
About the trial
What the trial wants to find out
This study aims to use functional near-infrared spectroscopy (fNIRS) to identify and quantify pain biomarkers during burn dressing changes and pain relief induced by virtual reality (VR).
The 2 groups in the trial
- VR-PATTreatment being tested
Participant wears the Pico Neo 3 Pro Eye headset and actively plays the VR-PAT game while also wearing the fNIRS, during their clinically scheduled burn dressing change.
- ControlNo study treatment, for comparison
Participant wears the fNIRS and can engage in standard distraction techniques, during their clinically scheduled burn dressing change.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Imaging Pain in a Virtual World: Neuroimaging Biomarkers for Assessing Brain Mechanisms Mediating Virtual Reality Pain Management in Children
- Plain-language title
- Virtual Reality Pain Relief Studied in Children With Burns and LeukemiaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06303687, who can take part
- Record updated
- 9 September 2026