Medication and bone care to prevent fall injuries in nursing facilities
Compares care plans to prevent falls in people healing from fractures.
Key facts
- Who runs it
- Duke University
- Where
- Boston and Durham, United StatesSee the 2 sites
- Trial code
- Registry title
- Prevention of Injury in Skilled Nursing Facilities Through Optimizing Medications
- Status
- Enrolling by invitation
- People taking part
- 3,780 people, planned
- Started
- 30 Sept 2024
- Expected to end
- 1 Jul 2028
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Deprescribing Care Model
- Bone Health Service Model
- Injury Prevention Service Model
- Record updated
- 16 January 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 65 or older who entered a skilled nursing facility after a hospital stay for a broken bone and finished a medication plan.
- Age
- 65 years or older
- Sex
- All sexes can join
- Disease stage
- A broken bone caused by weak bones (osteoporosis) that needed a hospital stay, followed by rehabilitation in a skilled nursing facility
- Earlier treatment
- Must have completed a medication optimization plan after admission to the facility
Main reasons for not taking part
- Broken bone not caused by weak bones (for example face, finger, skull, or at a tumor or infection site)
- Can receive hospice or palliative care
- Left the facility or died before the medication plan was completed
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Aged 65 years or greater
- Admitted to an enrolled SNF after hospitalized fracture
- Completion of a medication optimization plan
Who cannot take part
- Patient discharged or died prior to completion of a medication optimization plan
- Non-osteoporotic fracture (e.g. facial, digital, skull, at site of tumor or infection)
- Eligible for Hospice or palliative care
Where in United States
- Marcus Institute for Aging Research, Hebrew SeniorLifeBoston, United StatesEnrolling by invitation
- Duke University School of MedicineDurham, United StatesEnrolling by invitation
About the trial
What the trial wants to find out
The goal of this clinical trial is to compare three care models for optimizing medications and preventing falls with broken bones in patients receiving rehabilitation after a hospitalization for a broken bone.
Read full original descriptionShow less
The primary outcome is injurious falls, with secondary outcomes measuring how the process of care is changed and capturing patient-reported outcomes valued by stakeholders.
The main questions this study aims to answer are:
* Which of the three models is more effective in preventing falls with fractures? * What are the differences in patient-centered outcomes amongst the three models? These include pain, depression, anxiety, sleep, medication side effect burden, and fear of falling. * What are the differences in osteoporosis treatment and medication burden?
The three care models are: a Deprescribing Care Model designed to reduce or stop fall-related medications, a Bone Heath Service Model designed to provide osteoporosis evaluation and management, and an Injury Prevention Service Model offering both services.
42 SNFs will participate in this study. The three models will be incorporated into the routine care of patients at these facilities who are receiving rehabilitation after a hospitalization for a fracture. All care models will be delivered remotely to patients in the SNF and after they transition home by a post-fracture nurse consultant supported by an interprofessional team.
This study has three aims. See Detailed Description for more details. This ClinicalTrials.gov record represents the Comparative Effectiveness Aim of the protocol.
The 3 groups in the trial
- Deprescribing Care ModelExisting treatment, for comparison
In this pragmatic, cluster randomized crossover trial 42 Skilled Nursing Facilities (SNF) will each receive 6 months of each care model in random sequence. All patients with OP fracture admitted to the SNF within the intervention time period will receive the full designated care model, even if their stay in the SNF extends into the next intervention period.
- Bone Heath Service ModelExisting treatment, for comparison
In this pragmatic, cluster randomized crossover trial 42 Skilled Nursing Facilities (SNF) will each receive 6 months of each care model in random sequence. All patients with OP fracture admitted to the SNF within the intervention time period will receive the full designated care model, even if their stay in the SNF extends into the next intervention period.
Treatment: Bone Health Service Model
- Injury Prevention Service ModelExisting treatment, for comparison
In this pragmatic, cluster randomized crossover trial 42 Skilled Nursing Facilities (SNF) will each receive 6 months of each care model in random sequence. All patients with OP fracture admitted to the SNF within the intervention time period will receive the full designated care model, even if their stay in the SNF extends into the next intervention period.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Prevention of Injury in Skilled Nursing Facilities Through Optimizing Medications
- Plain-language title
- Medication and bone care to prevent fall injuries in nursing facilitiesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 16 January 2026