Compression stockinet for healing after leg amputation below the knee in peripheral arterial disease
Tests a special compression stockinet for wound healing after below-knee amputation.
Key facts
- Who runs it
- Mayo Clinic
- Where
- Rochester, United StatesSee the site
- Trial code
- Registry title
- Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease
- Status
- Recruiting
- People taking part
- 40 people, planned
- Started
- 7 Jul 2025
- Expected to end
- 31 Dec 2026
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Fuzzy Wale Compression Stockinet
- Record updated
- 14 January 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with peripheral arterial disease (poor blood flow in the legs) who are expected to have an amputation below the knee. It compares a Fuzzy Wale compression stockinet with the standard compression stocking for healing.
- Age
- Older than 18 years.
- Sex
- Men and women can join.
- Disease stage
- Peripheral arterial disease with a below-the-knee (transtibial) amputation expected.
- Biomarker or test result
- Transcutaneous partial pressure of oxygen (TCP02), a skin oxygen test, if it was done.
Main reasons for not taking part
- Known allergy to any part of the compression stockinet.
- Terminal illness, or current cancer treatment with chemotherapy.
- Not able to keep having care in Rochester.
- Not able to follow instructions or check the remaining limb.
- Pregnancy, or belonging to a vulnerable study group.
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- >18 years
- Male and female
- Transtibial amputation expected
- Peripheral arterial disease and Transcutaneous partial pressure of oxygen (TCP02, if performed)
- Ability of subject to give appropriate consent or have an appropriate representative available to do so
Who cannot take part
- Known allergies to any of the components of the compression
- Terminal illness or current cancer therapy with chemotherapy
- Inability to undergo ongoing care in Rochester
- Lack of cognitive ability to follow instructions or monitor residual limb
- Vulnerable study population
- Pregnancy
Where in United States
- Mayo ClinicRochester, United StatesContact: Vascular Research TeamTaking people
About the trial
What the trial wants to find out
The objective of this study is to determine if using Fuzzy Wale compression stockinet can assist in reducing the healing time and decrease costs in transtibial amputation patients as compared to standard of care treatment compression stocking.
The 2 groups in the trial
- Fuzzy Wale Compression StockinetTreatment being tested
Subjects with peripheral arterial disease requiring transtibial amputation will have Fuzzy Wale Compression Stockinet applied and utilized for 4-8 weeks post operatively or until prosthetic fitting and wound has achieved full durable healing.
- Standard of careNo study treatment, for comparison
Subjects with peripheral arterial disease requiring transtibial amputation will receive standard of care treatment compression stockinet.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Pilot Study of Fuzzy Wale Compression Stockinet to Evaluate Healing Following Transtibial Amputation for Peripheral Arterial Disease
- Plain-language title
- Compression stockinet for healing after leg amputation below the knee in peripheral arterial diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 14 January 2026