Tests CPAP breathing device in adults with severe asthma and sleep apnea
Tests whether a nighttime breathing machine helps asthma control in adults with sleep apnea.
Plain-language title generated from the registry record
Registry title: Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial
Key facts
- Where
- Barcelona, SpainSee the site
Where in Spain
- Hospital Clinic BarcelonaBarcelona, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital Clinic of Barcelona
- Trial code
- NCT06314477
- Record updated
- 21 September 2026
- Original description
The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)Read full original descriptionShow less
Effect of CPAP Treatment on Asthma Control in Patients With Severe Uncontrolled Asthma and Obstructive Sleep Apnea: The ASTHMA-SLEEP Study
The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)
Inclusion: Age >18 years; Diagnosis of severe uncontrolled asthma according to the criteria of the Spanish Asthma Management Guide (GEMA) or the Global Initiative for Asthma (GINA) and no hospitalizations the month prior to inclusion in the study; Apnea hypopnea rate greater than or equal to 15/hour; Punctuation in the Epworth Sleepiness Scale ≤10; Obtaining informed consent.
Exclusion: Previous treatment with CPAP; Unstable comorbidities or medications may interfere with asthma control; Other sleep disorders: narcolepsy, restless leg syndrome, chronic insomnia,; Resistant hypertension; Patient with central sleep apnea or Cheyne-Stokes respiration; Active Smoking; Pregnancy; Any process that reduces life expectancy to <1 year,; Any medical or social factor that may limit CPAP compliance.