NCT06316063Completed
Hemodynamic Effects of Apnoeic Oxygenation With High-flow Nasal Oxygen in Adults Undergoing Laryngeal Surgery
Hemodynamic Effects of Apnoeic Oxygenation With High-flow Nasal Oxygen in Adults Undergoing Laryngeal Surgery - a Randomised Study
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
During apnoeic oxygenation there is a continuous raise in carbon dioxide with subsequent respiratory acidosis. The hypercapnia and respiratory acidosis have several dose-related effects on both the systemic and the pulmonary circulation and the heart that ultimately, if unrecognised, can result in cardiovascular collapse and fatal arrhythmias. In our knowledge, no studies have investigated the haemodynamic effects of apnoeic oxygenation with HFNO. The general purpose of this project is to investigate haemodynamic alternations during apnoeic oxygenation with HFNO compared to mechanical ventilation in relatively healthy patients under general anaesthesia during laryngeal surgery.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 12 Mar 2024
- Start date
- 25 Mar 2024
- Primary completion date
- 26 Nov 2024
- Lead sponsor
- Region Stockholm
- NCT number
- NCT06316063
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 25 Mar 2024 to the primary completion date, 26 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Smokers or former smoker, last finished 6 months before inclusion
Other illness
- Neuromuscular disease
- Any pulmonary disease
Other
- NYHA-class \>1
- Pregnancy
- Severe gastric reflux
- Not capable of understanding study information and signing a written consent
Who the study is looking for
- Adult, ≥18 years old
- ASA 1-2
- BMI \< 30
- Planned for elective laryngeal surgery
Age in the registry: 18 years to 110 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karolinska universitetssjukhuset - Huddinge Coordinator of this site? Confirm its status | Stockholm | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.