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NCT06316063Completed

Hemodynamic Effects of Apnoeic Oxygenation With High-flow Nasal Oxygen in Adults Undergoing Laryngeal Surgery

Hemodynamic Effects of Apnoeic Oxygenation With High-flow Nasal Oxygen in Adults Undergoing Laryngeal Surgery - a Randomised Study

Source: ClinicalTrials.gov · Last updated 15 May 2026

Brief summary (registry, in English)

During apnoeic oxygenation there is a continuous raise in carbon dioxide with subsequent respiratory acidosis. The hypercapnia and respiratory acidosis have several dose-related effects on both the systemic and the pulmonary circulation and the heart that ultimately, if unrecognised, can result in cardiovascular collapse and fatal arrhythmias. In our knowledge, no studies have investigated the haemodynamic effects of apnoeic oxygenation with HFNO. The general purpose of this project is to investigate haemodynamic alternations during apnoeic oxygenation with HFNO compared to mechanical ventilation in relatively healthy patients under general anaesthesia during laryngeal surgery.

Status (registry)
Completed
Study type
Interventional
Enrollment
20 (actual)
First submitted
12 Mar 2024
Start date
25 Mar 2024
Primary completion date
26 Nov 2024
Lead sponsor
Region Stockholm
NCT number
NCT06316063

What you commit to

  • Study type: Interventional
  • Participants enrolled: 20
  • From 25 Mar 2024 to the primary completion date, 26 Nov 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Smokers or former smoker, last finished 6 months before inclusion

Other illness

  • Neuromuscular disease
  • Any pulmonary disease

Other

  • NYHA-class \>1
  • Pregnancy
  • Severe gastric reflux
  • Not capable of understanding study information and signing a written consent

Who the study is looking for

  • Adult, ≥18 years old
  • ASA 1-2
  • BMI \< 30
  • Planned for elective laryngeal surgery

Age in the registry: 18 years to 110 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Karolinska universitetssjukhuset - Huddinge
Coordinator of this site? Confirm its status
StockholmSwedenUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.