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Tests magnetic stimulation of the cerebellum to aid thinking after stroke

Tests repetitive magnetic stimulation of the cerebellum in adults with thinking problems after stroke.

Key facts

Who runs it
Zi-Xiao Li
Where
Beijing, ChinaSee the site
Trial code
Registry title
HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke
Status
Recruiting
People taking part
70 people, planned
Started
1 Jan 2025
Expected to end
1 Apr 2027
Type of study
Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
Treatments tested
  • iTBS group
  • control group
Record updated
2 July 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who had an ischemic stroke within the last 2 weeks and have problems with thinking and memory. It tests magnetic stimulation of the cerebellum.

Age
18 years or older
Sex
All sexes can join.
Disease stage
First ischemic stroke within 2 weeks, with a MoCA score below 26.

Main reasons for not taking part

  • Bleeding in the brain or around the brain (cerebral or subarachnoid hemorrhage)
  • A history of epilepsy before the stroke

The registry criteria, word for word

Show all 2 criteriaShow less

Who can take part

  • (1)ischemic stroke, with an initial incident occurring within 2 weeks;(2)MoCA<26

Who cannot take part

  • (1)Cerebral hemorrhage or subarachnoid hemorrhage;(2)A pre-existing history of epilepsy

Where in China

  • Beijing Tiantan HospitalBeijing, ChinaContact: Weili JiaTaking people

About the trial

What the trial wants to find out

The objective of this clinical trial is to investigate the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in the cerebellum for individuals with post-stroke cognitive impairment. Participants will undergo rTMS in the cerebellar hemisphere opposite the lesion site, once daily for a total of five days.

The 2 groups in the trial

  • iTBS groupTreatment being tested

    iTBS on the contralesional cerebellum

  • control groupPlacebo, for comparison

    shame stimulation on the contralesional cerebellum

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke
Plain-language title
Tests magnetic stimulation of the cerebellum to aid thinking after strokeGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
2 July 2025