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Weight loss and exercise program for Veterans after stroke

Tests a 15-week lifestyle program with exercise in Veterans who had a stroke.

Plain-language title generated from the registry record
Registry title: Weight Loss and ExeRcise for Post-stroke Veterans

Key facts

Where
Charleston, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 80 years old?

Source: NCT06322030, who can take part

Where in United States

  • Ralph H. Johnson VA Medical Center, Charleston, SCCharleston, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
VA Office of Research and Development
Trial code
NCT06322030
Record updated
15 May 2026
Original description
Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke.Read full original descriptionShow less

Enhancing Mobility and Psychosocial Function in Obese Veterans Following Stroke Via Weight Loss and ExeRcise (EMPOWER)

Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke.

Inclusion: A diagnosis of stroke at least 6 months prior; BMI > 30 kg/m2; Residual paresis in the lower extremity (Fugl-Meyer LE motor score <34); Ability to follow instructions, complete training and testing and to communicate exertion, pain and distress; Provision of informed consent; Individuals who meet inclusion criteria must complete an exercise tolerance test and be cleared for participation by the study cardiologist.

Exclusion: Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's; Dementia; History of DVT or pulmonary embolism within 6 months; Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions; Severe hypertension with systolic >200 mmHg and diastolic >110 mmHg at rest; Unable to ambulate at least 150 feet or experienced intermittent claudication while walking; Life expectancy <1 yr; Current enrollment in a rehabilitation trial to enhance motor or psychosocial recovery.

ClinicalTrials.gov NCT06322030