Comparing imaging methods to study blood flow in the brain in Moyamoya disease
Compares brain scans and blood sampling to study blood flow and disease activity in Moyamoya.
Plain-language title generated from the registry record
Registry title: Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients
Key facts
- Where
- Tübingen, GermanySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06330818, who can take part
Where in Germany
- University of Tuebingen, NeurosurgeryTübingen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital Tuebingen
- Trial code
- NCT06330818
- Record updated
- 26 September 2024
- Original description
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression.Read full original descriptionShow less
IMAGINE - Imaging in Moyamoya Disease
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression.
Main tasks are:
* Analysis of CO2-triggered BOLD fMRI for analysis of cerebral hemodynamics in comparison to H2 15O PET/CT * Analysis of longitudinal changes of contrast enhancement in vessel-wall imaging and correlation of disease activity with biosampling * Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients
Inclusion: Patients with suspicion of Moyamoya Disease; Patients able to understand the study and to give their informed consent.
Exclusion: Cerebral vascular disease caused by atherosclerosis; Renal insufficiency; Vasculitis; Contraindications to MRI; Contraindications to PET/CT; Pregnancy; Inability to give informed consent.