Hypoglossal Nerve Stimulation Therapy in Patients With Obstructive Sleep Apnea: Belgian Registry
Key facts
- Where
- Bruges and Edegem, BelgiumSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 99 years old?
Source: NCT06332404, who can take part
Where in Belgium
- Az Sint Jan BruggeBruges, BelgiumContact: Frederick Dochy, MDTaking people
- Antwerp University HospitalEdegem, BelgiumContact: Dorine Van Loo, MscTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University Hospital, Antwerp
- Trial code
- NCT06332404
- Record updated
- 15 September 2025
- Original description
Hypoglossal nerve stimulation (HNS) therapy (Inspire system) is intended for the treatment of patients with moderate to severe obstructive sleep apnea (OSA) who cannot be effectively treated with the first-line treatment options. Recently, the request for reimbursement of the Inspire system in Belgium was approved.Read full original descriptionShow less
Hypoglossal Nerve Stimulation (HNS) Therapy in Patients With Obstructive Sleep Apnea (OSA): Belgian Registry
Hypoglossal nerve stimulation (HNS) therapy (Inspire system) is intended for the treatment of patients with moderate to severe obstructive sleep apnea (OSA) who cannot be effectively treated with the first-line treatment options. Recently, the request for reimbursement of the Inspire system in Belgium was approved.
The aim is to create a multi-center registry of OSA patients that are treated with HNS (Inspire system) within routine clinical care in Belgium.
Inclusion: Any patient implanted with or receiving the Inspire HNS system and who is able to give informed consent is eligible to participate in the registry. A patient is eligible for HNS implantation if he/she meets the following criteria:; At least 18 years old at the time of implantation; The patient suffers from moderate to severe OSA (15 events/h ≤ AHI ≤ 65 events/h); The patient has failed, not tolerated or has a contraindication for continuous positive airway pressure (CPAP) and/or mandibular advancement device (MAD) therapy; Absence of complete concentric collapse of the level of the soft palate during Drug-Induced Sleep Endoscopy (DISE).
Exclusion: Surgery performed on the soft palate in the past three months before implantation; Body mass index (BMI) >32 kg/m²; Combined mixed and central AHI is more than 25% of the total AHI; Patients with complete concentric collapse at the level of the soft palate or any other anatomical deviation that could impede the proper functioning of HNS; Patients with severely impaired neurological control over the upper airway; Pregnancy.