NCT06338397Recruiting
Social & Affective Cognition in Alzheimer's Disease & Associated Disorders
Social & Affective Cognition as Determinant of Social Behavior in Alzheimer's Disease & Associated Disorders
Source: ClinicalTrials.gov · Last updated 30 Apr 2026
Brief summary (registry, in English)
Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 22 Mar 2024
- Start date
- 28 Jan 2025
- Primary completion date
- 28 Jan 2028
- Lead sponsor
- University Hospital, Lille
- Diseases
- Frontotemporal dementia, Alzheimer disease
- NCT number
- NCT06338397
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 28 Jan 2025 to the primary completion date, 28 Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants with excessive alcohol intake or drug abuse, in the judgment of the investigator;
Other illness
- Participants with dementia caused by a non-neurodegenerative disease, including patients with severe cerebrovascular risk factor load, in the judgment of the investigator;
- Participants with other neurodegenerative disease such as Lewy body dementia and Parkinson's disease;
- Participants with other serious neurological disorder such as brain tumor, stroke, epilepsy, hydrocephalus and any condition which contraindicates, in the investigator's judgment, entry to the study;
Other
- Participants who have contraindications to perform an MRI scan;
- Participants with significant sensory deficits that are not corrected by suitable devices.
- Participants who, in the opinion of the investigator, have a risk of non-compliance to the study procedures;
Who the study is looking for
- Men and women;
- 40 to 85 years of age (included);
- Registered with the French Social Security;
- Have a study partner. The study partner is required to complete several scales. If the subjects or their study partners are not able to drive, their transport fees will be reimbursed by the promotor.
- Fluent in French, able to read and write;
Age in the registry: 40 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lille University Hospital Coordinator of this site? Confirm its status | Lille | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.