Studying Social Thinking and Behavior in Alzheimer's and Related Brain Disorders
Studies how social and emotional thinking relates to behavior in people with Alzheimer's disease.
Plain-language title generated from the registry record
Registry title: Social & Affective Cognition in Alzheimer's Disease & Associated Disorders
Key facts
- Where
- Lille, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 85 years old?
Source: NCT06338397, who can take part
Where in France
- Lille University HospitalLille, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Lille
- Trial code
- NCT06338397
- Record updated
- 30 April 2026
- Original description
Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains.Read full original descriptionShow less
Social & Affective Cognition as Determinant of Social Behavior in Alzheimer's Disease & Associated Disorders
Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains.
Inclusion: Men and women; 40 to 85 years of age (included); Registered with the French Social Security; Have a study partner. The study partner is required to complete several scales. If the subjects or their study partners are not able to drive, their transport fees will be reimbursed by the promotor; Fluent in French, able to read and write.
Exclusion: Participants with excessive alcohol intake or drug abuse, in the judgment of the investigator; Participants with dementia caused by a non-neurodegenerative disease, including patients with severe cerebrovascular risk factor load, in the judgment of the investigator; Participants with other neurodegenerative disease such as Lewy body dementia and Parkinson's disease; Participants with other serious neurological disorder such as brain tumor, stroke, epilepsy, hydrocephalus and any condition which contraindicates, in the investigator's judgment, entry to the study; Participants who have contraindications to perform an MRI scan; Participants with significant sensory deficits that are not corrected by suitable devices; Participants who, in the opinion of the investigator, have a risk of non-compliance to the study procedures.