Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis
Where in Australia
- Box Hill · Box Hill HospitalTaking people
- Wantirna · Wantirna HealthTaking people
The registry text, word for word
A Blood Test for Dementia? A Cohort Study to Assess the Diagnostic Utility of Plasma Neurofilament Light Chain Protein in All-cause Dementia
This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network. The investigators will measure levels of a brain protein, Neurofilament light chain (Nfl), and assess changes in language using speech tests.
Participants will have a single blood test and speech test, and will be followed up at 12-months to complete questionnaires and cognitive scales over the phone. The speech test will also be completed again at 12-months.
Individuals at risk of a genetic dementia syndrome will be eligible to complete optional genetic testing involving an 'at home' saliva sample.
Inclusion: All patients presenting to Eastern Health services with a cognitive complaint or potential neurodegenerative disorder.
Exclusion: Prognosis <12 months; No cognitive complaint; Patients not involved within the single healthcare network.