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Blood Test for Early Detection of Bowel Polyps and Colorectal Cancer

Studies a blood test to find colon polyps and colorectal cancer early.

Plain-language title generated from the registry record
Registry title: Early Detection of Advanced Adenomas and Colorectal Cancer

Key facts

Where
Barcelona, SpainSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who had a colonoscopy when their blood was taken. It tests a blood test for early detection of advanced adenomas and colorectal cancer.

Age
18 Years or older
Sex
All sexes can join.
Disease stage
The record does not set one stage. It lists colorectal polyps, adenomas, and colorectal cancer stages I to IV.
Earlier treatment
At least one blood sample must have been taken before any treatment meant to remove all of the disease.

Main reasons for not taking part

  • Hereditary colorectal cancer syndromes (found through genetic testing)
  • Inflammatory bowel diseases
  • No written informed consent

Read by machine on 12 November 2026.

Where in Spain

  • Barcelona UniversityBarcelona, SpainContact: Francesc Balaguer, MD, PhDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
City of Hope Medical Center
Trial code
NCT06342440
Record updated
7 July 2026
Original description
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.Read full original descriptionShow less

A Liquid Biopsy Assay For The Non-Invasive Early Detection of Advanced Adenomas and Colorectal Cancer

This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.

Inclusion: All individuals included in the study need to have had a colonoscopy at the time of blood sampling; Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment; Received standard pathological and endoscopic diagnosis and assessment for cohort assignment.

Exclusion: Hereditary colorectal cancer syndromes (identified through genetic testing); Inflammatory bowel diseases; Lack of written informed consent.

ClinicalTrials.gov NCT06342440