Long-term outcomes of brain lesioning surgery for movement disorders
Records outcomes of brain lesioning surgery in people with dystonia, Parkinson disease or tremor.
Plain-language title generated from the registry record
Registry title: Lesioning Procedures for Movement Disorders
Key facts
- Where
- New Delhi, IndiaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The registry is looking for people with movement disorders who are being considered for a lesioning procedure in the brain.
- Age
- All ages can join.
- Sex
- All sexes can join.
- Disease stage
- People with movement disorders who are being considered for lesioning procedures.
Main reasons for not taking part
- People who do not give consent cannot join.
Read by machine on 12 November 2026.
Where in India
- All India Institute of Medical Sciences, New DelhiNew Delhi, IndiaContact: Arunmozhimaran Elavarasi, MD DMNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- All India Institute of Medical Sciences
- Trial code
- NCT06352268
- Record updated
- 8 April 2024
- Original description
Dystonia is a rare syndrome with varying etiologies. Similarly, tremor conditions refractory to medical management and disabling that they need surgical interventions are rare in our setting. So far there are no randomized controlled trials of pallidotomy for management of dystonia. There is scant literature on the long term efficacy and safety of Pallidotomy, thalamotomy and other such lesioning procedures in the management of movement disorders. The current literature is significantly plagued by publication bias as case reports with successful outcomes are likely to be selectively published in journals or conference abstracts. Lesioning procedures though seem to be effective are often considered to be risky, especially bilateral pallidotomy is not preferred by several centres. However, our center routinely performs simultaneous bilateral pallidotomy. To generate long term data on the efficacy and safety of lesioning procedures in rare diseases like dystonias especially the effect of functional neurosurgery on varying etiologies of the disease, robust registries are required which collect data on all consecutive patients who undergo the procedure.Read full original descriptionShow less
Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes of Patients Undergoing Lesioning Procedures for Movement Disorders - A Cohort Study and Registry
Dystonia is a rare syndrome with varying etiologies. Similarly, tremor conditions refractory to medical management and disabling that they need surgical interventions are rare in our setting. So far there are no randomized controlled trials of pallidotomy for management of dystonia. There is scant literature on the long term efficacy and safety of Pallidotomy, thalamotomy and other such lesioning procedures in the management of movement disorders. The current literature is significantly plagued by publication bias as case reports with successful outcomes are likely to be selectively published in journals or conference abstracts. Lesioning procedures though seem to be effective are often considered to be risky, especially bilateral pallidotomy is not preferred by several centres. However, our center routinely performs simultaneous bilateral pallidotomy. To generate long term data on the efficacy and safety of lesioning procedures in rare diseases like dystonias especially the effect of functional neurosurgery on varying etiologies of the disease, robust registries are required which collect data on all consecutive patients who undergo the procedure.
Inclusion: Patients with movement disorders admitted at the Neurology wards/attending clinics; Who are being considered for lesioning procedures; Of all ages and sexes.
Exclusion: Those who deny consent.