Comparing two stent strategies for heart attack patients undergoing artery opening procedures
Tests a drug-coated balloon approach against standard stents in adults with ST-elevation heart attack.
Plain-language title generated from the registry record
Registry title: Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI
Key facts
- Where
- A Coruña, Burgos, Castelló, Córdoba, Elche, Granada, Huelva, L'Hospitalet de Llobregat, Madrid, Málaga, Mérida, Pamplona, Santiago de Compostela, Seville, Tarragona, Terrassa, Valencia, Valladolid, and Zaragoza, SpainSee the 23 sites
Where in Spain
- Complejo Hospitalario Universitario de A CoruñaA Coruña, SpainTaking people
- Hospital Universitario De BurgosBurgos, SpainTaking people
- Consorcio Hospitalario Provincial de CastellonCastelló, SpainTaking people
- Hospital Universitario Reina Sofia de CórdobaCórdoba, SpainTaking people
- Hospital General Universitario de ElcheElche, SpainTaking people
- Hospital Universitario Clínico San CecilioGranada, SpainTaking people
- Hospital Universitario Juan Ramon JimenezHuelva, SpainTaking people
- Hospital Universitari de BellvitgeL'Hospitalet de Llobregat, SpainTaking people
- Hospital Universitario de la PrincesaMadrid, SpainTaking people
- Hospital Universitario La PazMadrid, SpainTaking people
- Hospital Universitario Puerta de Hierro - MajadahondaMadrid, SpainTaking people
- Hospital Universitario Regional de MálagaMálaga, SpainTaking people
- Hospital de MéridaMérida, SpainTaking people
- Hospital Universitario de NavarraPamplona, SpainTaking people
- Complejo Hospitalario Universitario De Santiago De CompostelaSantiago de Compostela, SpainTaking people
- Hospital Universitario Virgen del RocioSeville, SpainTaking people
- Hospital Universitari Joan XXIII de TarragonaTarragona, SpainTaking people
- Hospital Universitario Mutua de TerrassaTerrassa, SpainTaking people
- Consorcio Hospital General Universitario de ValenciaValencia, SpainTaking people
- Hospital Universitario Y Politecnico La FeValencia, SpainTaking people
- Hospital Clínico Universitario de ValladolidValladolid, SpainTaking people
- Hospital Clinico Universitario Lozano BlesaZaragoza, SpainTaking people
- Hospital Universitario Miguel ServetZaragoza, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital Universitario La Fe
- Trial code
- NCT06353594
- Record updated
- 28 May 2026
- Original description
The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI).Read full original descriptionShow less
Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With St-segment Elevation Myocardial Infarction (Copernican)
The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI).
Randomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies:
* Study group: reduced stent PCI strategy (DCB-based) * Control group: conventional PCI strategy (DES-based).
Inclusion: Patients presenting with STEMI and indication to undergo pPCI.
Exclusion: Patients with prior bypass graft lesions requiring PCI (culprit or non culprit lesions); Life expectancy <1 year due 1 to non-cardiac disease; Left main disease; Stent thrombosis; Untreatable coronary disease; Known allergy to aspirin, ticagrelor, prasugrel, clopidogrel, paclitaxel or sirolimus; Left ventricular ejection fraction <15%; Inability to provide informed consent; Cardiogenic shock; Patients with chronic total occlusions; Non-identified culprit lesion.