Under construction – not a live service
Sign in
Taking people in United KingdomNo phase

Brain blood flow in lacunar stroke before and after risk factor care

Measures brain blood flow in people with lacunar stroke, before and after risk factor care.

Plain-language title generated from the registry record
Registry title: The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke

Key facts

Where
Leicester, United KingdomSee the site

Where in United Kingdom

  • University Hospitals of Leicester NHS TrustLeicester, United KingdomTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of Leicester
Trial code
NCT06354881
Record updated
24 March 2025
Original description
The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke. Participants will be asked to undergo a simple brain blood flow assessment at their initial appointment, whereby they will be asked to sit and stand twice. The patients will then be asked for a follow-up assessment 4 weeks after, identical to the first. This will allow us to look at any changes in brain blood flow from before management of risk factors and 4 weeks after management of risk factors.Read full original descriptionShow less

Understanding the Relationship Between Controlling Risk Factors and Cerebral Haemodynamic Changes in Lacunar Stroke, and Its Interaction With Ageing

The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke. Participants will be asked to undergo a simple brain blood flow assessment at their initial appointment, whereby they will be asked to sit and stand twice. The patients will then be asked for a follow-up assessment 4 weeks after, identical to the first. This will allow us to look at any changes in brain blood flow from before management of risk factors and 4 weeks after management of risk factors.

Inclusion: Adults aged between 18-120 years; Diagnosis of lacunar stroke syndrome; New diagnosis or known diagnosis of hypertension and/or diabetes.

Exclusion: Those with poorly controlled medical comorbidities affecting cerebral haemodynamics. (eg., heart failure); Those who lack capacity can have a personal consultee consent to the study if they can still perform study requirements such as the sit-stand manoeuvre. Those who either cannot perform the manoeuvre or do not have a personal consultee to allow them to consent, are not able to take part.

ClinicalTrials.gov NCT06354881