Tests tenofovir disoproxil fumarate for early Parkinson's disease
Compares tenofovir disoproxil fumarate with no treatment in early Parkinson's patients.
Plain-language title generated from the registry record
Registry title: Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease
Key facts
- Where
- Hangzhou, ChinaSee the site
- Phase
- Phase 1
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06356662, who can take part
Where in China
- Guohua ZhaoHangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
- Trial code
- NCT06356662
- Record updated
- 17 February 2025
- Original description
To evaluate the efficacy and safety of tenofovir disoproxil fumarate in the treatment of Parkinson's disease. The changes of motor symptoms and the occurrence of adverse reactions in early Parkinson's disease patients who took tenofovir disoproxil fumarate and did not take Tenofovir disoproxil fumarate at different time points were compared.Read full original descriptionShow less
Efficacy and Safety of Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease
To evaluate the efficacy and safety of tenofovir disoproxil fumarate in the treatment of Parkinson's disease. The changes of motor symptoms and the occurrence of adverse reactions in early Parkinson's disease patients who took tenofovir disoproxil fumarate and did not take Tenofovir disoproxil fumarate at different time points were compared.
Inclusion: 1: Parkinson's disease: Hoehn Yahr= 1 to 2.5 2: MMSE score≥24.
Exclusion: 1: essential tremor, stroke, epilepsy and other well-defined neurological disorders; 2: Or have received deep brain stimulation and other brain surgery; 3: Abnormal liver and kidney function; 4: Infected with chronic hepatitis B or AIDS (HIV-1 infection); 5: Severe depression, schizophrenia, other psychiatric disorders or drug dependence; 6: Other serious physical diseases such as heart, lung, liver, kidney disease, blood disease and malignant tumor; 7: Pregnant or lactating women and seniors over 65 years of age; 8: Allergy or other contraindications to the investigational drug.