Studies gut bacteria over time in people with chronic heart failure
Follows gut bacteria and body changes in adults with weakened-heart failure over time.
Plain-language title generated from the registry record
Registry title: Gut Microbiome Profiling in Patients With Chronic Heart Failure
Key facts
- Where
- Stanford, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT06361524, who can take part
Where in United States
- Stanford UniversityStanford, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Stanford University
- Trial code
- NCT06361524
- Record updated
- 16 May 2025
- Original description
The goal of this observational study is to learn about the composition and function of the gut microbiome in adults with chronic heart failure with reduced ejection fraction. The main questions the study aims to answer are:Read full original descriptionShow less
Longitudinal Gut Microbiome and Host Multi-omic Profiling in Patients With Chronic Heart Failure
The goal of this observational study is to learn about the composition and function of the gut microbiome in adults with chronic heart failure with reduced ejection fraction. The main questions the study aims to answer are:
1. How does the gut microbiome and its interactions with the host change over time in adults with chronic heart failure? 2. How do these changes relate to heart failure disease severity and complications?
Inclusion: Heart failure with reduced ejection fraction (left ventricular ejection fraction less than 50%); Non-ischemic cardiomyopathy; Body mass index (BMI) 18-40 kg/m2.
Exclusion: Current or recent (within 4 weeks) use of systemic antibiotics, commercial probiotics, immunosuppressive or immunomodulatory medications; Treated diabetes; Advanced kidney disease; Significant gastrointestinal disease including any history of inflammatory bowel disease; History of extensive bowel resection; Active malignancy or systemic chemotherapy within the past 12 months; Active infection; Cirrhosis; Pregnancy/lactation.