The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus
Key facts
- Who runs it
- Al-Azhar University
- Where
- Egypt1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- Phase
- Phase 4
- People taking part
- 50 people enrolled
- Started
- 1 May 2024
- Ended
- 1 Oct 2025
- Type of study
- Interventional, 5 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Triamcinolone Acetonide 0.1% Oint
- Tacrollimus Topical
- Selenium
- Selenium & Triamcinolone Acetonide 0.1% Oint
- Selenium& Tacrollimus topical
- Record updated
- 31 December 2025
Who can take part
- Age
- 20 years to 55 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- clinical diagnosis of OLP
Who cannot take part
- lichenoid reaction from medication '
- any systemic autoimmune disease
- Pregnancy
- smokers
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
evaluate clinically and biochemically the efficacy of topically applied selenium as complementary or alternative to triamcinolone acetonide 0.1% and tacrolimus 0.1% in patients with oral lichen planus.
The 5 groups in the trial
- group I (triamcinolone)Placebo, for comparison
ten patients with oral lichen planus, will receive topical triamcinolone acetonide 0.1% four times per day for six weeks.
Treatment: Triamcinolone Acetonide 0.1% Oint
- group II (tacrollimus)Placebo, for comparison
ten patients with oral lichen planus, will receive topical tacrolimus 0.1% four times per day for six weeks.
Treatment: Tacrollimus Topical
- group III (selenium)Treatment being tested
ten patients with oral lichen planus, will receive topical selenium four times per day for six weeks.
Treatment: Selenium
- group IV (selenium + triamcinolone )Treatment being tested
: ten patients with oral lichen planus, will receive topical selenium combined with topical triamcinolone acetonide 0.1% three times per day for each for six weeks
Treatment: Selenium & Triamcinolone Acetonide 0.1% Oint
- group V ( selenium + tacrollimus)Treatment being tested
ten patients with oral lichen planus, will receive topical selenium combined with topical tacrolimus 0.1% three times per day for each for six weeks.
Treatment: Selenium& Tacrollimus topical
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus (Randomized Clinical Trial)
- Record updated
- 31 December 2025