Home Visual Training for Young People With Vision Loss After Brain Tumour
Tests a home headset training program for vision loss in people aged 10 to 40.
Key facts
- Who runs it
- University Health Network, Toronto
- Where
- Calgary, Montreal, Québec, Toronto, and Vancouver, CanadaSee the 5 sites
- Trial code
- Registry title
- Visual Telerehabilitation in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour
- Status
- Not yet recruiting
- People taking part
- 50 people, planned
- Started
- 1 Jun 2024
- Expected to end
- 1 Jun 2027
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Audiovisual stimulation
- Record updated
- 12 April 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 10 to 40 with hemianopsia (loss of half of the visual field) after a brain tumour. They would do a visual training program at home with a virtual reality headset.
- Age
- 10 to 40 years old.
- Sex
- Both men and women can join.
- Disease stage
- Hemianopsia diagnosed more than 18 months ago, after a brain tumour. The tumour must have been stable for more than 18 months, with or without treatment.
- Earlier treatment
- People who have had earlier vision rehabilitation cannot join.
- Biomarker or test result
- A positive online hearing test at 125 Hz (for research purposes only).
Main reasons for not taking part
- Eye disease
- Cloudiness in both eyes that blocks the eye field test
- Use of psychoactive drugs, for fun or as medicine
- A history of vertigo or dizziness
- 3 cybersickness scores in a row below 25 at the start
The registry criteria, word for word
Show all 17 criteriaShow less
Who can take part
- Diagnosed hemianopsia (\> 18 months)
- History of a diagnosis of brain tumour
- Being stable for the tumour for \>18 months (either on therapy or not)
- Male and female
- 10 - 40 years old
- Ability to follow the visual and auditory stimuli and training instructions
- Online auditory test positive (-5dbHL to 60dbHL range) at 125 Hz (for research purposes only)
- Home Wi-Fi access
Who cannot take part
- Recreational or medicinal consumption of psychoactive drugs
- Prior vision rehabilitation interventions
- Ocular disease
- History of vertigo or dizziness
- \< 10 years old
- \> 40 years old
- Both eyes with media opacity that impairs microperimetry testing
- Inability to perform during testing and training
- 3 consecutive VRISE (cybersickness) scores \< 25 at inclusion
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 10 and 40 years old?
Where in Canada
- Alberta Children's HospitalCalgary, CanadaContact: Lucie Lafay-Cousin, MDNo longer taking part
- Centre Hospitalier Universitaire Sainte-JustineMontreal, CanadaContact: Sebastien Perreault, MDNo longer taking part
- CHU de QuebecQuébec, CanadaContact: Valerie Larouche, MDNo longer taking part
- The Hospital for Sick ChildrenToronto, CanadaContact: Eric Bouffet, MDNo longer taking part
- British Columbia Children's HospitalVancouver, CanadaContact: Sylvia Cheng, MDNo longer taking part
About the trial
What the trial wants to find out
Brain malignancies are the most common cause of death from cancer in the pediatric population and a major source of morbidity amongst survivors. Many children with a brain tumour often suffer from visual field defects (hemianopia) dramatically impacting their daily life with poorer social interaction, difficulties learning, playing sports and engaging with peers. Practically, they bump into people and objects and have problems in finding their way in unfamiliar places and in detecting incoming objects in their blind field. There is growing recognition of the diverse and deep impact of hemianopia on physical and mental health, quality of life, and social outcomes of the affected individuals and their family. However, despite the frequent impact of brain tumours on the visual function and functional vision, ophthalmologic evaluations are not standard of care for all brain tumour patients and there are no standardized protocols of vision loss management in the pediatric population with hemianopia. There is an unmet need of restoring perception in the blind field in individuals with hemianopia consecutive to pediatric brain tumor.
Read full original descriptionShow less
Our laboratory has developed a visual rehabilitation procedure based on the combination of adaptative audio and visual target tracking in a 3D environment in virtual reality. Participants perform audiovisual stimulation at home in a headset, with remote control from the laboratory. Preliminary on data on paediatric patients with hemianopia consecutive to a brain tumour indicate feasibility and potential effectiveness of a 6-week Re:Vision program on visual fields, visual perception and quality of life.
Our objective is to evaluate the effectiveness of Re:Vision, an 8-week visual telerehabilitation program, on visual perception in 50 individuals aged 10-40 years old with hemianopia consecutive to a pediatric brain tumor in a phase IIa/b multi-centric clinical study across Canada.
This intervention provides more equitable access to individuals, with the ability to receive rehabilitation therapy at home without supervision by a healthcare professional, meaning that Canadians living outside urban centres could take advantage of specialized therapies with remote supervision. This is the first study that could lead to a major change in the management of these patients. It could open the door for visual rehabilitation strategies to other population of visually impaired children, significantly impacting public health strategies.
The 2 groups in the trial
- Intervention - No InterventionTreatment being tested
8-week audiovisual stimulation followed by 8-week no intervention
Treatment: Audiovisual stimulation
- No Intervention - InterventionNo study treatment, for comparison
8-week no intervention followed by 8-week audiovisual stimulation
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effectiveness of a Visual Telerehabilitation Program on Visual Perception in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour.
- Plain-language title
- Home Visual Training for Young People With Vision Loss After Brain TumourGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06362434, who can take part
- Record updated
- 12 April 2024