NCT06363760Enrolling by invitation
A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301
Source: ClinicalTrials.gov · Last updated 2 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this study is to evaluate the long-term safety and efficacy of EDIT-301 in participants with severe sickle cell disease (SCD) or transfusion-dependent β-thalassemia (TDT) who have received EDIT-301.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 54 (estimated)
- First submitted
- 9 Apr 2024
- Start date
- 17 Jun 2024
- Primary completion date
- Aug 2040
- Lead sponsor
- Editas Medicine, Inc.
- Diseases
- Sickle cell disease, Thalassaemia
- NCT number
- NCT06363760
What you commit to
- Study type: Observational
- Planned participants: 54
- From 17 Jun 2024 to the primary completion date, Aug 2040
- 18 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Participant is still actively enrolled in an EDIT-301 treatment study and has not yet met eligibility for long term follow-up in this study.
Who the study is looking for
- Participant must have received an EDIT-301 infusion as part of a clinical study.
- Participant or legal representative/guardian (if applicable) must sign and date the informed consent form (ICF) or assent, if applicable for this long-term follow-up study.
Age in the registry: 12 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (18)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ottawa Hospital Research Institute Coordinator of this site? Confirm its status | Ottawa | Canada | Unknown status |
| Princess Margaret Cancer Centre - University Health Network Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Children's Healthcare of Atlanta Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Children's Hospital Colorado Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
| Atrium Health Coordinator of this site? Confirm its status | Charlotte | United States | Unknown status |
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| Nationwide Children's Hospital Coordinator of this site? Confirm its status | Columbus | United States | Unknown status |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Cook Children's Coordinator of this site? Confirm its status | Fort Worth | United States | Unknown status |
| University of Minnesota Coordinator of this site? Confirm its status | Minneapolis | United States | Unknown status |
| Tristar Medical Group Children's Specialists/Sarah Cannon Center for Blood Cancers Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| Smilow Cancer Hospital Coordinator of this site? Confirm its status | New Haven | United States | Unknown status |
| Columbia University Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Columbia University Medical Center - Department of Pediatrics Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| UCSF Benioff Children s Hospital Coordinator of this site? Confirm its status | Oakland | United States | Unknown status |
| Children's Hospital of Philadelphia Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Johns Hopkins All Children's Hospital Coordinator of this site? Confirm its status | St. Petersburg | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.