Tests magnetic brain stimulation for depression with memory, sleep and interest problems
Tests repeated magnetic brain stimulation in adults with depression and related symptoms.
Plain-language title generated from the registry record
Registry title: Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression
Key facts
- Where
- Krakow, PolandSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 65 with a moderate or severe depressive episode, with sleep problems and memory or concentration problems. It tests magnetic brain stimulation (rTMS).
- Age
- 18 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Moderate or severe depressive episode (ICD-10) without psychotic symptoms. Hamilton Depression Rating Scale score between 20 and 35 points.
- Biomarker or test result
- Athens Insomnia Scale score of 8 or more. Score of 3 or more points in items 4 and 21 of the Beck Depression Inventory 2. Memory and concentration problems that began around the time depression began.
Main reasons for not taking part
- Reasons not to have magnetic stimulation, such as metal parts in the head, pregnancy or epilepsy
- Psychotic symptoms at the time of joining
- Suicidal thoughts or attempts in the 3 months before joining
Read by machine on 11 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06363981, who can take part
Where in Poland
- The Education of Research and Development Center, Babinski Clinical HospitalKrakow, PolandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Jakub Antczak
- Trial code
- NCT06363981
- Record updated
- 15 October 2024
- Original description
Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat. rTMS is a relatively novel treatment option, whose therapeutic potential is still investigated and optimized. The aim of this study is to assess the effect of rTMS applied over two stimulation sites on cognitive impairment, anhedonia and sleep disorders in depression.Read full original descriptionShow less
Multisite Repetitive Transcranial Magnetic Stimulation for Mood, Cognitive Impairment, Anhedonia and Disordered Sleep in Depressive Disorder
Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat. rTMS is a relatively novel treatment option, whose therapeutic potential is still investigated and optimized. The aim of this study is to assess the effect of rTMS applied over two stimulation sites on cognitive impairment, anhedonia and sleep disorders in depression.
Inclusion: severe or moderate depressive episode (according to international classification of diseases (ICD)-10) without psychotic symptoms at the time of inclusion; Hamilton Depression Rating Scale between between 20 and 35 points at inclusion; The score in the Athens Insomnia Scale eight or more; The score of three or more points in items 4 and 21 of the Beck Depressions Inventory 2; Complaining about problems with memory and concentration timely related with the onset of depression.
Exclusion: Suicidal ideations and/or attempts within three months prior to inclusion; Contraindications to transcranial magnetic stimulation, including ferromagnetic elements in head, pregnancy and epilepsy; Psychotic symptoms at the time of inclusion.